CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
KE6325000
-
CHEMICAL NAME :
-
Ergoline, 8,9-didehydro-6,8-dimethyl-
-
CAS REGISTRY NUMBER :
-
548-42-5
-
BEILSTEIN REFERENCE NO. :
-
0024966
-
LAST UPDATED :
-
199709
-
DATA ITEMS CITED :
-
5
-
MOLECULAR FORMULA :
-
C16-H18-N2
-
MOLECULAR WEIGHT :
-
238.36
-
WISWESSER LINE NOTATION :
-
T C6656 1A P GN LM DUTT&&J E1 G1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
25 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
25500 ug/kg
-
TOXIC EFFECTS :
-
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - cyanosis
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
DOSE :
-
50 mg/kg
-
SEX/DURATION :
-
female 1-5 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
DOSE :
-
20 mg/kg
-
SEX/DURATION :
-
female 3-4 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - other measures of fertility
MUTATION DATA
-
TYPE OF TEST :
-
Mutation in microorganisms
-
TEST SYSTEM :
-
Bacteria - Salmonella typhimurium
-
DOSE/DURATION :
-
2 umol/plate
-
REFERENCE :
-
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 47,1811,1987
|
CAS#:1935-33-7