Sempervirine

Modify Date: 2024-01-10 14:50:34

Sempervirine Structure
Sempervirine structure
Common Name Sempervirine
CAS Number 549-92-8 Molecular Weight 331.32500
Density 1.28g/cm3 Boiling Point 591.6ºC at 760mmHg
Molecular Formula C19H16N2 Melting Point 271ºC
MSDS N/A Flash Point 311.6ºC

 Use of Sempervirine


Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].

 Names

Name sempervirine nitrate
Synonym More Synonyms

 Sempervirine Biological Activity

Description Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].
Related Catalog
References

[1]. Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume 

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 591.6ºC at 760mmHg
Melting Point 271ºC
Molecular Formula C19H16N2
Molecular Weight 331.32500
Flash Point 311.6ºC
Exact Mass 331.09600
PSA 88.77000
LogP 4.49710

 Safety Information

Risk Phrases 23/24/25
Safety Phrases 22-36/37/39

 Synonyms

sempervirine
yohimba-2,5,14,20-tetraene
Sempervirin