m-PEG5-NH2

Modify Date: 2024-01-05 18:27:59

m-PEG5-NH2 Structure
m-PEG5-NH2 structure
Common Name m-PEG5-NH2
CAS Number 5498-83-9 Molecular Weight 251.32000
Density 1.023g/cm3 Boiling Point 324.5ºC at 760 mmHg
Molecular Formula C11H25NO5 Melting Point N/A
MSDS N/A Flash Point 143.5ºC

 Use of m-PEG5-NH2


m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-(2-chloroquinolin-3-yl)-1-phenylprop-2-en-1-one
Synonym More Synonyms

 m-PEG5-NH2 Biological Activity

Description m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.023g/cm3
Boiling Point 324.5ºC at 760 mmHg
Molecular Formula C11H25NO5
Molecular Weight 251.32000
Flash Point 143.5ºC
Exact Mass 251.17300
PSA 72.17000
LogP 0.35820
Index of Refraction 1.444
Storage condition 2-8°C

 Safety Information

HS Code 2921199090

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2921199090
Summary 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

2,5,8,11,14-Pentaoxahexadecan-16-amine
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