Propoxycaine (hydrochloride)

Modify Date: 2024-01-11 16:13:39

Propoxycaine (hydrochloride) Structure
Propoxycaine (hydrochloride) structure
Common Name Propoxycaine (hydrochloride)
CAS Number 550-83-4 Molecular Weight 330.85000
Density N/A Boiling Point 434.4ºC at 760mmHg
Molecular Formula C16H27ClN2O3 Melting Point N/A
MSDS N/A Flash Point 216.5ºC

 Use of Propoxycaine (hydrochloride)


Propoxycaine hydrochloride is the hydrochloride salt form of Propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity.Target: sodium channelPropoxycaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. This results in a loss of sensation.

 Names

Name 2-(diethylamino)ethyl 4-amino-2-propoxybenzoate,hydrochloride
Synonym More Synonyms

 Propoxycaine (hydrochloride) Biological Activity

Description Propoxycaine hydrochloride is the hydrochloride salt form of Propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity.Target: sodium channelPropoxycaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. This results in a loss of sensation.
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 Chemical & Physical Properties

Boiling Point 434.4ºC at 760mmHg
Molecular Formula C16H27ClN2O3
Molecular Weight 330.85000
Flash Point 216.5ºC
Exact Mass 330.17100
PSA 64.79000
LogP 3.93940
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG3066000
CHEMICAL NAME :
Benzoic acid, 4-amino-2-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride
CAS REGISTRY NUMBER :
550-83-4
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C16-H26-N2-O3.Cl-H
MOLECULAR WEIGHT :
330.90
WISWESSER LINE NOTATION :
3OR CZ FVO2N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,133,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7417 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,269,1958

 Safety Information

RIDADR UN 2811 6.1 / PGIII

 Synonyms

Pravocaine hydrochloride
EINECS 208-988-7
WIN 3459
Propoxycaine HCl
Ravocaine hydrochloride
Blockain
4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride
BENZOIC ACID,4-AMINO-2-PROPOXY-,2-(DIETHYLAMINO)ETHYL ESTER,MONOHYDROCHLORIDE
Propoxycaine Hyrochloride
Propoxycaine hydrochloride
Propoxycaine (hydrochloride)
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