N-Succinimidyl maleimidoacetate

Modify Date: 2024-01-02 14:17:08

N-Succinimidyl maleimidoacetate Structure
N-Succinimidyl maleimidoacetate structure
Common Name N-Succinimidyl maleimidoacetate
CAS Number 55750-61-3 Molecular Weight 252.180
Density 1.6±0.1 g/cm3 Boiling Point 430.1±47.0 °C at 760 mmHg
Molecular Formula C10H8N2O6 Melting Point 174-175ºC
MSDS Chinese USA Flash Point 213.9±29.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of N-Succinimidyl maleimidoacetate


AMAS is a heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.

 Names

Name Maleimidoacetic Acid N-Hydroxysuccinimide Ester
Synonym More Synonyms

 N-Succinimidyl maleimidoacetate Biological Activity

Description AMAS is a heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
Related Catalog
Target

Alkyl/ether

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 430.1±47.0 °C at 760 mmHg
Melting Point 174-175ºC
Molecular Formula C10H8N2O6
Molecular Weight 252.180
Flash Point 213.9±29.3 °C
Exact Mass 252.038239
PSA 101.06000
LogP -2.21
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.620

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
HS Code 2925190090

 Synthetic Route

~83%

N-Succinimidyl maleimidoacetate Structure

N-Succinimidyl ...

CAS#:55750-61-3

Literature: Wang, Tzu-Pin; Ko, Ni Chien; Su, Yu-Chih; Wang, Eng-Chi; Severance, Scott; Hwang, Chi-Ching; Shih, Ying Ting; Wu, Min Hui; Chen, Yen-Hsu Bioconjugate Chemistry, 2012 , vol. 23, # 12 p. 2417 - 2433

~32%

N-Succinimidyl maleimidoacetate Structure

N-Succinimidyl ...

CAS#:55750-61-3

Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

1H-Pyrrole-2,5-dione, 1-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-
(2,5-dioxopyrrolidin-1-yl) 2-(2,5-dioxopyrrol-1-yl)acetate
MFCD00133523
1-{2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl}-1H-pyrrole-2,5-dione
N-Succinimidyl maleimidoacetate
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