L-Lysine

Modify Date: 2024-01-02 08:14:23

L-Lysine structure	Common Name	L-Lysine
	CAS Number	56-87-1	Molecular Weight	146.188
	Density	1.1±0.1 g/cm3	Boiling Point	311.5±32.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₄N₂O₂	Melting Point	215 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	142.2±25.1 °C

Use of L-Lysine

L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

Name	L-lysine
Synonym	More Synonyms

Description	L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	L-lysine (150 mg/kg) promotes, but not initiates, bladder cancer. The administration of L-lysine to rats submitted to colovesical cystoplasty accelerates the development of transitional metaplasia of the intestinal epithelium[1]. L-lysine (10 mg/kg) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity[2].
References	[1]. Santos AMD, et al. Transitional metaplasia in intestinal epithelium of rats submitted to intestinal cystoplasty and treatment with L -lysine. Acta Cir Bras. 2017 Apr;32(4):297-306. [2]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193.

Density	1.1±0.1 g/cm3
Boiling Point	311.5±32.0 °C at 760 mmHg
Melting Point	215 °C (dec.)(lit.)
Molecular Formula	C₆H₁₄N₂O₂
Molecular Weight	146.188
Flash Point	142.2±25.1 °C
Exact Mass	146.105530
PSA	89.34000
LogP	-1.04
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.503
Storage condition	Store at RT.
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	H2O: 0.1 g/mL, clear, colorless

L-Lysine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OL5540000

CHEMICAL NAME :: Lysine, L-

CAS REGISTRY NUMBER :: 56-87-1

BEILSTEIN REFERENCE NO. :: 1722531

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C6-H14-N2-O2

MOLECULAR WEIGHT :: 146.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 138 gm/kg

SEX/DURATION :: female 5-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 72450 mg/kg

SEX/DURATION :: female 10-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 90450 mg/kg

SEX/DURATION :: female 10-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 81 gm/kg

SEX/DURATION :: female 10-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 44 gm/kg

SEX/DURATION :: female 5-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	OL5540000
HS Code	2922411000

Precursor 4
CAS#:70-54-2 DL-Lysine CAS#:405-39-0 Z-Lys(Z)-OH CAS#:2212-75-1 Z-Lys-OH CAS#:105047-45-8 Fmoc-Lys-OH
DownStream 10
CAS#:111061-54-2 Fmoc-Lys(Trt)-OH CAS#:576-19-2 Biocytin CAS#:5910-89-4 2,3-Dimethylpyrazine CAS#:13360-65-1 2-Ethyl-3,5-dim...
CAS#:54410-83-2 5-Isobutyl-2,3-... CAS#:13925-07-0 2-Ethyl-3,5-dim... CAS#:22047-26-3 2-acetyl-6-meth... CAS#:22047-27-4 2-acetyl-5-meth...
CAS#:70303-42-3 3,5-dimethyl-2-... CAS#:13360-64-0 2-Ethyl-5-methy...

HS Code	2922411000
Summary	HS: 2922411000. 2,6-diaminohexanoic acid. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:5.0%. general tariff:20.0%

Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine.

FEBS J. 281(24) , 5498-512, (2014)

D-Phosphoglycerate dehydrogenase (PGDH) catalyzes the first committed step of the phosphorylated serine biosynthesis pathway. Here, we report for the first time, the crystal structures of Type IIIK PG...

ALD1 Regulates Basal Immune Components and Early Inducible Defense Responses in Arabidopsis.

Mol. Plant Microbe Interact. 28(4) , 455-66, (2015)

Robust immunity requires basal defense machinery to mediate timely responses and feedback cycles to amplify defenses against potentially spreading infections. AGD2-LIKE DEFENSE RESPONSE PROTEIN 1 (ALD...

Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.

Arch. Biochem. Biophys. 550-551 , 58-66, (2014)

The mechanism of Mycobacterium smegmatis G (MbsG), a flavin-dependent l-lysine monooxygenase, was investigated under steady-state and rapid reaction conditions using primary and solvent kinetic isotop...

L-lys

Lisina [Spanish]

6-Amino-L-norleucine

(+)-S-Lysine

Lys

L-Lysine (9CI)

(l)-lysine

(S)-(+)-Lysine

Aminutrin

Lysine acid

(S)-a,e-Diaminocaproic Acid

Lysinum [Latin]

(S)-lysine

Lysine

2,6-Diaminohexanoic acid, (S)-

FEMA 3847

(S)-2,6-diamino-Hexanoic acid

L-Lysine

Lysine, L-

MFCD00064433

EINECS 200-294-2

H-Lys-OH

L-lysine zwitterion

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: L-Lysine
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BioBioPha
China
Product Name: L-Lysine
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China
Product Name: L-Lysine
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DC Chemicals Limited
China
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China
Product Name: L-Lysine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: L-Lysine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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L-Lysine

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