BMS 566419

Modify Date: 2024-01-17 09:40:11

BMS 566419 Structure
BMS 566419 structure
Common Name BMS 566419
CAS Number 566161-24-8 Molecular Weight 487.56900
Density N/A Boiling Point N/A
Molecular Formula C28H30FN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS 566419


BMS-566419 is an acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase (IMPDH). Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme in the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility for the research of transplant rejection[1].

 Names

Name N-[2-[6-(4-ethylpiperazin-1-yl)pyridin-3-yl]propan-2-yl]-2-fluoro-9-oxo-10H-acridine-3-carboxamide
Synonym More Synonyms

 BMS 566419 Biological Activity

Description BMS-566419 is an acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase (IMPDH). Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme in the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility for the research of transplant rejection[1].
Related Catalog
References

[1]. Watterson SH, et al. Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419). J Med Chem. 2007;50(15):3730-3742.

 Chemical & Physical Properties

Molecular Formula C28H30FN5O2
Molecular Weight 487.56900
Exact Mass 487.23800
PSA 84.82000
LogP 4.60010

 Synonyms

unii-9688e11zq0
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: BMS-566419
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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