Therafectin

Modify Date: 2024-01-14 15:30:17

Therafectin Structure
Therafectin structure
Common Name Therafectin
CAS Number 56824-20-5 Molecular Weight 341.82800
Density 1.21g/cm3 Boiling Point 431ºC at 760mmHg
Molecular Formula C14H28ClNO6 Melting Point 255ºC
MSDS N/A Flash Point 214.5ºC

 Use of Therafectin


Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC). Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes[1][2].

 Names

Name Amiprilose
Synonym More Synonyms

 Therafectin Biological Activity

Description Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC). Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes[1][2].
Related Catalog
References

[1]. Wang XK, et al. Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma. J Cancer. 2020 Aug 25;11(20):6140-6156.  

[2]. Hadden JW. Effects of isoprinosine, levamisole, muramyl dipeptide, and SM1213 on lymphocyte and macrophage function in vitro. Cancer Treat Rep. 1978 Nov;62(11):1981-5.  

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 431ºC at 760mmHg
Melting Point 255ºC
Molecular Formula C14H28ClNO6
Molecular Weight 341.82800
Flash Point 214.5ºC
Exact Mass 341.16100
PSA 80.62000
LogP 0.35490
Index of Refraction 1.521
Storage condition -20°C

 Safety Information

Risk Phrases R23/24/25
Safety Phrases 22-26-36-45

 Synthetic Route

~68%

Therafectin Structure

Therafectin

CAS#:56824-20-5

Literature: Tripathi, R. P.; Singh, V.; Khan, A. R.; Bhaduri, A. P.; Saxena, G.; Chandra, K. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 9 p. 791 - 795

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Therafectin Structure

Therafectin

CAS#:56824-20-5

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 9 p. 791 - 795

~%

Therafectin Structure

Therafectin

CAS#:56824-20-5

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 9 p. 791 - 795

 Synonyms

1,2-O-Isopropylidene-3-O-[3-(N,N-dimethylamino)propyl]-a-D-glucofuranose
SM-1213
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