U 44069 structure
|
Common Name | U 44069 | ||
---|---|---|---|---|
CAS Number | 56985-32-1 | Molecular Weight | 350.49 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 519.7±35.0 °C at 760 mmHg | |
Molecular Formula | C21H34O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 176.1±19.4 °C | |
Symbol |
GHS02, GHS07 |
Signal Word | Danger |
Use of U 44069U-44069 is a stable prostaglandin (PG) H2 analogue and a potent vasoconstrictor. U-44069 induces Ca influx at preglomerular vessels[1]. |
Name | 9,11-Dideoxy-9α,11α-epoxymethanoprostaglandin F2α |
---|---|
Synonym | More Synonyms |
Description | U-44069 is a stable prostaglandin (PG) H2 analogue and a potent vasoconstrictor. U-44069 induces Ca influx at preglomerular vessels[1]. |
---|---|
Related Catalog | |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 519.7±35.0 °C at 760 mmHg |
Molecular Formula | C21H34O4 |
Molecular Weight | 350.49 |
Flash Point | 176.1±19.4 °C |
Exact Mass | 350.245697 |
PSA | 66.76000 |
LogP | 3.88 |
Vapour Pressure | 0.0±3.1 mmHg at 25°C |
Index of Refraction | 1.548 |
Symbol |
GHS02, GHS07 |
---|---|
Signal Word | Danger |
Hazard Statements | H225-H319-H336 |
Supplemental HS | Repeated exposure may cause skin dryness or cracking. |
Precautionary Statements | P210-P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P403 + P235 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xn |
Risk Phrases | 20/21/22 |
Safety Phrases | 22-36 |
RIDADR | UN1231 - class 3 - PG 2 - Methyl acetate, solution |
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.
Prostaglandins Leukot. Essent. Fatty Acids 76(5) , 299-308, (2007) The role of endothelin, PAF and thromboxane A2 in airway hyperreactivity (AHR) to carbachol induced by ovalbumin sensitization and challenge in Balb/c mice was investigated. Ovalbumin sensitization an... |
|
Glibenclamide inhibits agonist-induced vasoconstriction of placental chorionic plate arteries.
Placenta 27(6-7) , 660-8, (2006) Preliminary data suggest that K(ATP) channels may be expressed in placental arteries and veins [Wareing M, Turner C, Greenwood SL, Baker PN, Fyfe GK. Expression of mRNA encoding K+ channels in chorion... |
|
Substrate binding is the rate-limiting step in thromboxane synthase catalysis.
J. Biol. Chem. 276(18) , 14737-43, (2001) Thromboxane synthase (TXAS) is a "non-classical" cytochrome P450. Without any need for an external electron donor, or for a reductase or molecular oxygen, it uses prostaglandin H2 (PGH2) to catalyze e... |
5-Heptenoic acid, 7-[(1S,4R,5S,6R)-5-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl]-, (5Z)- |
(Z)-7-[(1R,2S,3R,4S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxabicyclo[2.2.1]heptan-3-yl]hept-5-enoic acid |
(5Z)-7-{(1S,4R,5S,6R)-5-[(1E,3S)-3-Hydroxy-1-octen-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl}-5-heptenoic acid |
MFCD00135237 |