DMBA

Modify Date: 2024-01-02 18:28:39

DMBA Structure
DMBA structure
Common Name DMBA
CAS Number 57-97-6 Molecular Weight 256.341
Density 1.1±0.1 g/cm3 Boiling Point 463.5±15.0 °C at 760 mmHg
Molecular Formula C20H16 Melting Point 122-123 °C(lit.)
MSDS Chinese USA Flash Point 227.3±14.5 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

 Use of DMBA


DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models[1].

 Names

Name 7,12-dimethyltetraphene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 463.5±15.0 °C at 760 mmHg
Melting Point 122-123 °C(lit.)
Molecular Formula C20H16
Molecular Weight 256.341
Flash Point 227.3±14.5 °C
Exact Mass 256.125214
LogP 6.83
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.729
Storage condition 2-8°C

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H301 + H311 + H331-H350-H370
Precautionary Statements P201-P260-P280-P301 + P310-P311
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C: Corrosive;
Risk Phrases R22
Safety Phrases S53-S36/37-S45-S62-S61-S60
RIDADR UN 3077 9/PG 3
WGK Germany 3
RTECS DP4500000
Packaging Group III
Hazard Class 6.1(b)

 Synthetic Route

 Articles141

More Articles
The licorice flavonoid isoliquiritigenin reduces DNA-binding activity of AhR in MCF-7 cells.

Chem. Biol. Interact. 221 , 70-6, (2014)

Licorice is derived from the rhizomes of Glycyrrhiza glabra. It has been used for confectioneries or culinary purposes. The rhizomes contain many flavonoidal compounds that have been shown to be biolo...

Core-shell nanoparticulate formulation of gemcitabine: lyophilization, stability studies, and in vivo evaluation.

Drug Deliv Transl Res 4 , 439-51, (2015)

Core-shell nanoparticulate formulation of gemcitabine was prepared by incorporating gemcitabine in a hydrophilic bovine serum albumin (BSA) core surrounded by hydrophobic poly(DL-lactic acid-co-glycol...

Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.

J. Pharmacol. Exp. Ther. 350(1) , 79-88, (2014)

Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis. A transforming growth factor (TGF)-β1-induced i...

 Synonyms

EINECS 200-359-5
DMBA
7,12-Dimethyltetraphene
MFCD00003600
7,12-Dimethylbenzo[a]anthracene
Benz[a]anthracene, 7,12-dimethyl-
7,12-Dimethylbenz[a]anthracene
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