4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester

Modify Date: 2024-01-02 19:26:03

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure
4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester structure
Common Name 4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
CAS Number 571189-16-7 Molecular Weight 308.333
Density 1.258 Boiling Point 480.1±45.0 °C at 760 mmHg
Molecular Formula C14H20N4O4 Melting Point N/A
MSDS N/A Flash Point 244.1±28.7 °C

 Names

Name tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.258
Boiling Point 480.1±45.0 °C at 760 mmHg
Molecular Formula C14H20N4O4
Molecular Weight 308.333
Flash Point 244.1±28.7 °C
Exact Mass 308.148468
PSA 91.49000
LogP 1.85
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.562

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~78%

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure

4-(6-Nitro-3-py...

CAS#:571189-16-7

Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/95159 A1, 2006 ; Location in patent: Page/Page column 77-78 ; WO 2006/095159 A1

~93%

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure

4-(6-Nitro-3-py...

CAS#:571189-16-7

Literature: Calienni, John Vincent; Chen, Guang-Pei; Gong, Baoqing; Kapa, Prasad Koteswara; Saxena, Vishal Patent: US2012/115878 A1, 2012 ; Location in patent: Page/Page column 9 ;

~79%

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure

4-(6-Nitro-3-py...

CAS#:571189-16-7

Literature: Imaeda, Yasuhiro; Kawamoto, Tetsuji; Tobisu, Mamoru; Konishi, Noriko; Hiroe, Katsuhiko; Kawamura, Masaki; Tanaka, Toshimasa; Kubo, Keiji Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 6 p. 3125 - 3140

~%

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure

4-(6-Nitro-3-py...

CAS#:571189-16-7

Literature: WO2012/97682 A1, ; Page/Page column 158 ;

~%

Detail
Literature: US2003/149001 A1, ; US 20030149001 A1

~%

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure

4-(6-Nitro-3-py...

CAS#:571189-16-7

Literature: Journal of Medicinal Chemistry, , vol. 48, # 7 p. 2388 - 2406

~%

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester Structure

4-(6-Nitro-3-py...

CAS#:571189-16-7

Literature: WO2012/97682 A1, ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
1,1-Dimethylethyl 4-(6-nitro-3-pyridinyl)-1-piperazinecarboxylate
tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
1-Piperazinecarboxylic acid, 4-(6-nitro-3-pyridinyl)-, 1,1-dimethylethyl ester
T6N DNJ AVOX1&1&1 D- ET6NJ BNW
2-Methyl-2-propanyl 4-(6-nitro-3-pyridinyl)-1-piperazinecarboxylate
4-(6-nitro-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester
4-(6-nitro-3-pyridinyl)-1-piperazinecarboxylic acid,1,1-dimethylethyl ester
1-Boc-4-(6-nitropyridin-3-yl)piperazine
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