Avicularin

Modify Date: 2024-01-02 17:32:39

Avicularin Structure
Avicularin structure
Common Name Avicularin
CAS Number 572-30-5 Molecular Weight 434.350
Density 1.9±0.1 g/cm3 Boiling Point 855.4±65.0 °C at 760 mmHg
Molecular Formula C20H18O11 Melting Point 240-243ºC
MSDS Chinese USA Flash Point 305.8±27.8 °C

 Use of Avicularin


Avicularin is a bio-active flavonoid from plants, anti-inflammatory, anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF κB (p65), COX 2 and PPAR γ activities[1][2].

 Names

Name avicularin
Synonym More Synonyms

 Avicularin Biological Activity

Description Avicularin is a bio-active flavonoid from plants, anti-inflammatory, anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF κB (p65), COX 2 and PPAR γ activities[1][2].
Related Catalog
References

[1]. Vo VA, et al. Avicularin Inhibits Lipopolysaccharide-Induced Inflammatory Response by Suppressing ERK Phosphorylation in RAW 264.7 Macrophages. Biomol Ther (Seoul). 2012 Nov;20(6):532-7.

[2]. Wang Z, et al. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities. Mol Med Rep. 2019 Jun;19(6):5417-5423.

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 855.4±65.0 °C at 760 mmHg
Melting Point 240-243ºC
Molecular Formula C20H18O11
Molecular Weight 434.350
Flash Point 305.8±27.8 °C
Exact Mass 434.084900
PSA 190.28000
LogP 2.06
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.802
Storage condition 2-8C

 Safety Information

RIDADR NONH for all modes of transport

 Articles12

More Articles
Protective effect of components isolated from Lindera erythrocarpa against oxidative stress-induced apoptosis of H9c2 cardiomyocytes.

Phytother Res. 25(11) , 1612-7, (2011)

Eight compounds were isolated from the methanol fraction of Lindera erythrocarpa and assessed for their ability to protect H9c2 cardiomyocytes against oxidative stress-induced cell death. Three of the...

Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava.

Biosci. Biotechnol. Biochem. 74 , 878-880, (2010)

Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease in...

[Determination of avicularin in Polygonum aviculare L].

Yao Xue Xue Bao 18(9) , 700-4, (1983)

 Synonyms

4H-1-Benzopyran-4-one, 3-(α-L-arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-
Fenicularin
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl α-L-arabinofuranoside
Quercetin 3-α-L-arabinofuranoside
Avicularin
QUERCETIN-3-ARABINOSIDE
Avicularoside
Avicularine
Avicularin,Quercetin 3-alpha-L-arabinofuranoside
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