Vitamin K4

Modify Date: 2024-01-02 12:04:59

Vitamin K4 Structure
Vitamin K4 structure
Common Name Vitamin K4
CAS Number 573-20-6 Molecular Weight 258.269
Density 1.2±0.1 g/cm3 Boiling Point 388.9±30.0 °C at 760 mmHg
Molecular Formula C15H14O4 Melting Point 113 °C
MSDS Chinese USA Flash Point 195.1±23.0 °C
Symbol GHS05
GHS05
Signal Word Danger

 Use of Vitamin K4


Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system.

 Names

Name Menadiol Diacetate
Synonym More Synonyms

 Vitamin K4 Biological Activity

Description Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system.
Related Catalog
References

[1]. Jiang Y, et al. Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway. Pharmazie. 2013 Jun;68(6):442-8.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 388.9±30.0 °C at 760 mmHg
Melting Point 113 °C
Molecular Formula C15H14O4
Molecular Weight 258.269
Flash Point 195.1±23.0 °C
Exact Mass 258.089203
PSA 52.60000
LogP 2.67
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.580
Storage condition 2~8 ℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ5250000
CHEMICAL NAME :
1,4-Naphthalenediol, 2-methyl-, diacetate
CAS REGISTRY NUMBER :
573-20-6
BEILSTEIN REFERENCE NO. :
1991457
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H14-O4
MOLECULAR WEIGHT :
258.29
WISWESSER LINE NOTATION :
L66J BOV1 C1 EOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,111,1942

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338 + P310
Hazard Codes Xi
RIDADR NONH for all modes of transport
RTECS QJ5250000

 Precursor & DownStream

Precursor  0

DownStream  2

 Articles2

More Articles
Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway. Jiang Y, et.al.

Pharmazie 68 , 442-448, (2013)

One-Pot Hydroacetylation of Menadione (Vitamin K3) to Menadiol Diacetate (Vitamin K4) by Heterogeneous Catalysis. Dobrinescu C, et.al.

Adv. Synth. Catal. 354 , 1301-1306, (2012)

 Synonyms

2-Methyl-1,4-naphthalenediol Diacetate
MFCD00021469
2-Methyl-1,4-naphthalenediyl diacetate
(4-acetyloxy-3-methylnaphthalen-1-yl) acetate
1,4-Naphthalenediol, 2-methyl-, diacetate
Kappaxan (VAN)
2-Methylnaphthalene-1,4-diyl diacetate
EINECS 209-352-1
Vitamin K4
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