Aureothricin

Modify Date: 2024-01-04 17:34:59

Aureothricin Structure
Aureothricin structure
Common Name Aureothricin
CAS Number 574-95-8 Molecular Weight 242.31800
Density 1.48g/cm3 Boiling Point 479.1ºC at 760 mmHg
Molecular Formula C9H10N2O2S2 Melting Point N/A
MSDS N/A Flash Point 243.6ºC

 Use of Aureothricin


Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].

 Names

Name N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)propanamide
Synonym More Synonyms

 Aureothricin Biological Activity

Description Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].
Related Catalog
Target

Bacteral[1]

References

[1]. Li B, et al. Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics. Nat Prod Rep. 2014 Jul;31(7):905-23.

 Chemical & Physical Properties

Density 1.48g/cm3
Boiling Point 479.1ºC at 760 mmHg
Molecular Formula C9H10N2O2S2
Molecular Weight 242.31800
Flash Point 243.6ºC
Exact Mass 242.01800
PSA 111.07000
LogP 2.61110
Index of Refraction 1.694

 Synonyms

propionopyrrothine
Aureothricin
Anzeothricin
4-methyl-6-propionylamino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-one
N-(4-methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-propionamide
N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-propionamid
Farcinicin
Propiopyvothine
Aurethricin