DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II)

Modify Date: 2024-04-02 13:45:33

DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II) Structure
DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II) structure
Common Name DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II)
CAS Number 57948-13-7 Molecular Weight 386.13600
Density N/A Boiling Point 262.3ºC at 760 mmHg
Molecular Formula C7H8Cl2N2Pt Melting Point N/A
MSDS N/A Flash Point 132.1ºC

 Names

Name cis-Dichloro(3,4-diaminotoluene)platinum(II)
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 262.3ºC at 760 mmHg
Molecular Formula C7H8Cl2N2Pt
Molecular Weight 386.13600
Flash Point 132.1ºC
Exact Mass 384.97100
PSA 24.06000
LogP 3.39990

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2497220
CHEMICAL NAME :
Platinum (II), dichloro(4-methyl-o-phenylenediammine)-
CAS REGISTRY NUMBER :
57948-13-7
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H10-Cl2-N2-Pt
MOLECULAR WEIGHT :
388.18
WISWESSER LINE NOTATION :
ZR BZ D1 &G-PT-G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
2500 nmol/L
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980

 Synthetic Route

~%

DICHLORO(4-METHYL-o-PHENYLENEDI-AMMINE)PLATINUM(II) Structure

DICHLORO(4-METH...

CAS#:57948-13-7

Literature: Rosenheim, A.; Haendler, W. Ber., 1926 , vol. 59, p. 1387 - 1390 Full Text Show Details Gmelin Handbook: Pt: MVol.D, 122, page 278 - 280

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

dichloro-1,3 methoxycarbonylhydrazono-2 propane