EHNA.HCl

Modify Date: 2024-01-02 17:46:03

EHNA.HCl Structure
EHNA.HCl structure
Common Name EHNA.HCl
CAS Number 58337-38-5 Molecular Weight 313.826
Density 1.27g/cm3 Boiling Point 478.2ºC at 760mmHg
Molecular Formula C14H24ClN5O Melting Point N/A
MSDS USA Flash Point 243ºC

 Use of EHNA.HCl


EHNA hydrochloride is a specific inhibitor of adenosine deaminase, prevents dAdo degradation and increases mitochondrial dATP levels in fibroblasts[1].

 Names

Name EHNA hydrochloride
Synonym More Synonyms

 EHNA.HCl Biological Activity

Description EHNA hydrochloride is a specific inhibitor of adenosine deaminase, prevents dAdo degradation and increases mitochondrial dATP levels in fibroblasts[1].
Related Catalog
References

[1]. Blázquez-Bermejo C, et al. Increased dNTP pools rescue mtDNA depletion in human POLG-deficient fibroblasts. FASEB J. 2019 Jun;33(6):7168-7179.

 Chemical & Physical Properties

Density 1.27g/cm3
Boiling Point 478.2ºC at 760mmHg
Molecular Formula C14H24ClN5O
Molecular Weight 313.826
Flash Point 243ºC
Exact Mass 313.166931
PSA 89.85000
LogP 3.68400

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Articles34

More Articles
Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes

Biochim. Biophys. Acta 1833(12) , 3228-36, (2013)

Autophagic flux is an important process during autophagy maturation in coronary arterial myocytes (CAMs). Here, we defined the role and molecular mechanism of the motor protein dynein in the regulatio...

Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance.

Am. J. Physiol. Lung Cell. Mol. Physiol. 301(2) , L171-80, (2011)

Mucociliary clearance, vital to lung clearance, is dependent on cilia beat frequency (CBF), coordination of cilia, and the maintenance of periciliary fluid. Adenosine, the metabolic breakdown product ...

Adenosine accelerates the healing of diabetic ischemic ulcers by improving autophagy of endothelial progenitor cells grown on a biomaterial.

Sci. Rep. 5 , 11594, (2015)

Endothelial progenitor cells (EPCs) seeded on biomaterials can effectively promote diabetic ischemic wound healing. However, the function of transplanted EPCs is negatively affected by a high-glucose ...

 Synonyms

(2S,3R)-3-(6-Amino-9H-purin-9-yl)-2-nonanol hydrochloride (1:1)
9H-Purine-9-ethanol, 6-amino-β-hexyl-α-methyl-, monohydrochloride
9H-Purine-9-ethanol, 6-amino-.β.-hexyl-.α.-methyl-, monohydrochloride
9H-Purine-9-ethanol, 6-amino-β-hexyl-α-methyl-, (αS,βR)-, hydrochloride (1:1)
(2S,3R)-3-(6-Amino-9H-purin-9-yl)nonan-2-ol hydrochloride (1:1)
EHNA hydrochloride
EHNA.HCl