Higenamine structure
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Common Name | Higenamine | ||
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CAS Number | 5843-65-2 | Molecular Weight | 271.311 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 522.4±50.0 °C at 760 mmHg | |
Molecular Formula | C16H17NO3 | Melting Point | 208-210℃ | |
MSDS | N/A | Flash Point | 209.6±20.7 °C |
Use of HigenamineHigenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine (Norcoclaurine) has anti-apoptotic effects[1][2]. |
Name | (RS)-norcoclaurine |
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Synonym | More Synonyms |
Description | Higenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine (Norcoclaurine) has anti-apoptotic effects[1][2]. |
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Related Catalog | |
Target |
β2-AR[1] |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 522.4±50.0 °C at 760 mmHg |
Melting Point | 208-210℃ |
Molecular Formula | C16H17NO3 |
Molecular Weight | 271.311 |
Flash Point | 209.6±20.7 °C |
Exact Mass | 271.120850 |
PSA | 72.72000 |
LogP | 1.41 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.666 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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~99% Higenamine CAS#:5843-65-2 |
Literature: Pesnot, Thomas; Gershater, Markus C.; Ward, John M.; Hailes, Helen C. Advanced Synthesis and Catalysis, 2012 , vol. 354, # 16 p. 2997 - 3008 |
~% Higenamine CAS#:5843-65-2 |
Literature: Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 2997 - 3008 |
~% Higenamine CAS#:5843-65-2 |
Literature: Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 2997 - 3008 |
~% Higenamine CAS#:5843-65-2 |
Literature: Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 2997 - 3008 |
~% Higenamine CAS#:5843-65-2 |
Literature: Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 2997 - 3008 |
~% Higenamine CAS#:5843-65-2 |
Literature: Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 2997 - 3008 |
Higenamine |
1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisochinolin-6,7-diol |
(R,S)-norcoclaurine |
(+-)-O-Demethylcoclaurine |
Coclaurine,O-demethyl-,(+-) |
1-(p-hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline |
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]- |
(+-)-Demethylcoclaurine |
rac-norcoclaurine |
1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol |
(±)-HIGENAMINE |
Norcoclaurine |
1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol |
1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol |
UNII:TBV5O16GAP |
Isoquinolin-6,7-diol, 1,2,3,4-tetrahydro-1-[4-hydroxybenzyl]- |
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-, (±)- |
6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-,(+-) |