EMA [Ethidium monoazide bromide]

Modify Date: 2024-01-05 10:24:31

EMA [Ethidium monoazide bromide] Structure
EMA [Ethidium monoazide bromide] structure
Common Name EMA [Ethidium monoazide bromide]
CAS Number 58880-05-0 Molecular Weight 420.30500
Density N/A Boiling Point N/A
Molecular Formula C21H18BrN5 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of EMA [Ethidium monoazide bromide]


Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells[1].

 Names

Name 8-azido-5-ethyl-6-phenylphenanthridin-5-ium-3-amine,bromide
Synonym More Synonyms

 EMA [Ethidium monoazide bromide] Biological Activity

Description Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells[1].
Related Catalog
References

[1]. Nogva HK, et al. Ethidium monoazide for DNA-based differentiation of viable and dead bacteria by 5'-nuclease PCR. Biotechniques. 2003 Apr;34(4):804-8, 810, 812-3.

 Chemical & Physical Properties

Molecular Formula C21H18BrN5
Molecular Weight 420.30500
Exact Mass 419.07500
PSA 79.65000
LogP 2.52936

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SF7941850
CHEMICAL NAME :
Phenanthridinium, 3-amino-8-azido-5-ethyl-6-phenyl-, bromide
CAS REGISTRY NUMBER :
58880-05-0
LAST UPDATED :
199707
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H18-N5.Br
MOLECULAR WEIGHT :
420.35
WISWESSER LINE NOTATION :
T B666 HKJ EZ H2 IR& LNNN &E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
2 umol/L/30M
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 56,21,1977

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
RTECS SF7941850

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 Synonyms

Phenanthridinium,3-amino-8-azido-5-ethyl-6-phenyl-,bromide
MFCD00213986
3-Amino-8-azido-5-ethyl-6-phenylphenanthridinium bromide
Ethidium azide bromide
Ethidium bromide monoazide
Ethidium monoazide bromide
Monoazido ethidium bromide
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