11R-VIVIT structure
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Common Name | 11R-VIVIT | ||
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CAS Number | 592517-80-1 | Molecular Weight | 3573.15 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C147H259N67O36S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of 11R-VIVIT11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. |
Name | 11R-VIVIT |
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Description | 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. |
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Related Catalog |
Molecular Formula | C147H259N67O36S |
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Molecular Weight | 3573.15 |