Cinchonine hydrochloride

Modify Date: 2024-01-02 14:03:23

Cinchonine hydrochloride structure	Common Name	Cinchonine hydrochloride
	CAS Number	5949-11-1	Molecular Weight	330.852
	Density	N/A	Boiling Point	464.5ºC at 760 mmHg
	Molecular Formula	C₁₉H₂₃ClN₂O	Melting Point	208-218ºC(lit.)
	MSDS	N/A	Flash Point	N/A

Use of Cinchonine hydrochloride

Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound present in Cinchona bark. Cinchonine hydrochloride activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1].

Name	Cinchonine monohydrochloride hydrate
Synonym	More Synonyms

Description	Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound present in Cinchona bark. Cinchonine hydrochloride activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Jin ZL, et al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.

Boiling Point	464.5ºC at 760 mmHg
Melting Point	208-218ºC(lit.)
Molecular Formula	C₁₉H₂₃ClN₂O
Molecular Weight	330.852
Exact Mass	330.149902
PSA	36.36000
LogP	3.90450

Cinchonine hydrochloride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD2962020

CHEMICAL NAME :: Cinchonan-9-ol, monohydrochloride, (9S)-

CAS REGISTRY NUMBER :: 5949-11-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H22-N2-O.Cl-H

MOLECULAR WEIGHT :: 330.89

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 720 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2550093

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992

Hazard Codes	Xi,Xn
Risk Phrases	R20/21/22
Safety Phrases	36/37-26
RIDADR	UN 1544
WGK Germany	3
RTECS	GD2962020
Packaging Group	III
Hazard Class	6.1(b)

Cinchonan-9-ol, (9S)-, hydrochloride (1:1)

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cinchonan-9-ol,monohydrochloride, (9s)-

cinchonine hydrochloride hydrate

cinchonine hydrochloride dihydrate

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cinchonine monohydrochloride dihydrate

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Cinchonan-9-ol, chloride, hydrogen salt, (9S)- (1:1)

l-cinchonine hydrochloride

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Cinchonine hydrochloride
Price: ￥978.0/25g
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Cinchonine hydrochloride
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cinchonine hydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥1000/20 mg

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