Dihydro Cyclosporin A

Modify Date: 2024-01-20 12:01:16

Dihydro Cyclosporin A structure	Common Name	Dihydro Cyclosporin A
	CAS Number	59865-15-5	Molecular Weight	1204.627
	Density	1.0±0.1 g/cm3	Boiling Point	1285.3±65.0 °C at 760 mmHg
	Molecular Formula	C₆₂H₁₁₃N₁₁O₁₂	Melting Point	120-125ºC
	MSDS	N/A	Flash Point	731.1±34.3 °C

Use of Dihydro Cyclosporin A

Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1].

Name	Dihydro Cyclosporin A
Synonym	More Synonyms

Description	Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1].
Related Catalog	Research Areas >> Infection
References	[1]. Zheng ZW, et al. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A. Parasit Vectors. 2020 Feb 21;13(1):94.

Density	1.0±0.1 g/cm3
Boiling Point	1285.3±65.0 °C at 760 mmHg
Melting Point	120-125ºC
Molecular Formula	C₆₂H₁₁₃N₁₁O₁₂
Molecular Weight	1204.627
Flash Point	731.1±34.3 °C
Exact Mass	1203.857056
PSA	278.80000
LogP	3.67
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.465
Storage condition	-20°C

Precursor 3
CAS#:59865-13-3 Cyclosporin A CAS#:121584-52-9 6-[(3R,4R)-3-(A... CAS#:83563-94-4
DownStream 0

6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A

<DH-MeBmt>cyclosporin

dihydro-CSA

DIHYDROCYCLOSPORIN A

Dihydrocyclosporin

(3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-Ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

(3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)

(3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]

1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S)-

Cyclosporin Impurity 10