Name | Dihydro Cyclosporin A |
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Synonyms |
6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A
<DH-MeBmt>cyclosporin dihydro-CSA DIHYDROCYCLOSPORIN A Dihydrocyclosporin (3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-Ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone (3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) (3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S)- Cyclosporin Impurity 10 |
Description | Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1]. |
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Related Catalog | |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 1285.3±65.0 °C at 760 mmHg |
Melting Point | 120-125ºC |
Molecular Formula | C62H113N11O12 |
Molecular Weight | 1204.627 |
Flash Point | 731.1±34.3 °C |
Exact Mass | 1203.857056 |
PSA | 278.80000 |
LogP | 3.67 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.465 |
Storage condition | -20°C |
Precursor 3 | |
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DownStream 0 |