AHR-5333

Modify Date: 2024-02-26 15:38:00

AHR-5333 structure	Common Name	AHR-5333
	CAS Number	60284-71-1	Molecular Weight	509.58400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₃F₂NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AHR-5333

AHR-5333 is a selective human blood neutrophil 5-lipoxygenase inhibitor. AHR-5333 exhibits potent, long-acting activity in rat and guinea pig in vivo models of immediate hypersensitivity[1].

Name	1-[4-[3-[4-[bis(4-fluorophenyl)-hydroxymethyl]piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanone
Synonym	More Synonyms

Description	AHR-5333 is a selective human blood neutrophil 5-lipoxygenase inhibitor. AHR-5333 exhibits potent, long-acting activity in rat and guinea pig in vivo models of immediate hypersensitivity[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
Target	60284-71-1
References	[1]. J M Yanni, et al. Effects of AHR-5333, a new potential antiallergy compound, in in vivo models of immediate hypersensitivity. Int Arch Allergy Appl Immunol. 1988;85(4):428-33. [2]. G. Graff, et al. 1-[4-[3-[4-[Bis (4-fluorophenyl) hydroxymethyl]-1-piperidinyl] propoxy]-3]-methoxyphenyl] ethanone (AHR-5333): A selective human blood neutrophil 5-lipoxygenase inhibitor. Prostaglandins. Volume 38, Issue 4, October 1989, Pages 473-496

Molecular Formula	C₃₀H₃₃F₂NO₄
Molecular Weight	509.58400
Exact Mass	509.23800
PSA	59.00000
LogP	5.53090

Ahr 5333