H-Tyr-D-Ala-Gly-Phe-Met-NH2

Modify Date: 2024-01-08 14:43:04

H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure
H-Tyr-D-Ala-Gly-Phe-Met-NH2 structure
 Common Name H-Tyr-D-Ala-Gly-Phe-Met-NH2
CAS Number 61090-95-7 Molecular Weight 586.70300
Density 1.286 g/cm3 Boiling Point 1057.4ºC at 760 mmHg
Molecular Formula C28H38N6O6S Melting Point N/A
MSDS N/A Flash Point 593.3ºC

 Use of H-Tyr-D-Ala-Gly-Phe-Met-NH2


[D-Ala2]-Met-Enkephalinamide, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism. [D-Ala2]-Met-Enkephalinamide has analgesic properties[1][2].

 Names

Name 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide
Synonym More Synonyms

 H-Tyr-D-Ala-Gly-Phe-Met-NH2 Biological Activity

Description [D-Ala2]-Met-Enkephalinamide, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism. [D-Ala2]-Met-Enkephalinamide has analgesic properties[1][2].
Related Catalog
In Vivo [D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism in Sprague-Dawley rats[1]. Animal Model: Male Sprague-Dawley rats (250-320 g)[1] Dosage: 10, 50, 100, 150, and 200 mg/kg Administration: Intracerebroventrical injection Result: Decreased in bile flow that ranged from 12% to 41%. Decreased bicarbonate secretion into bile.

 Chemical & Physical Properties

Density 1.286 g/cm3
Boiling Point 1057.4ºC at 760 mmHg
Molecular Formula C28H38N6O6S
Molecular Weight 586.70300
Flash Point 593.3ºC
Exact Mass 586.25700
PSA 231.04000
LogP 2.29780
Index of Refraction 1.601

 Synthetic Route

Boc Tyr D.Ala Gly Phe Met NH2 structure

Boc Tyr D.Ala G...

CAS#:66960-03-0

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H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
(2R)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]propanoic acid structure

(2R)-2-[[(2S)-3...

CAS#:71591-34-9

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H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
Boc-Tyr-D-Ala-Gly-OH structure

Boc-Tyr-D-Ala-Gly-OH

CAS#:64410-47-5

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H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
Boc-L-Tyr-D-Ala-OMe structure

Boc-L-Tyr-D-Ala-OMe

CAS#:74392-86-2

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H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine methyl ester structure

N-(tert-butylox...

CAS#:78537-07-2

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H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycyl-L-phenylalanyl-L-methionine methyl ester structure

N-(tert-butylox...

CAS#:67581-53-7

~%

H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
Boc Tyr D.Ala Gly Phe OH structure

Boc Tyr D.Ala G...

CAS#:67582-10-9

~%

H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
Methyl tert-butyloxycarbonyltyrosyl-(D)alanylglycylphenylalaninate structure

Methyl tert-but...

CAS#:66444-26-6

~%

H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
Boc-(L)(α-Me)Tyr-OH structure

Boc-(L)(α-Me)Tyr-OH

CAS#:74825-83-5

~%

H-Tyr-D-Ala-Gly-Phe-Met-NH2 Structure

H-Tyr-D-Ala-Gly...

CAS#:61090-95-7

Literature: Audigier; Mazarguil; Gout; Cros European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177

 Synonyms

DAME
[D-Ala2]Met-enkephalinamide
D-Enkephalin
Met-enkephalinamide,ala(2)
[D-Ala2-Met5]enkephalinamide
Methionine-enkephalinamide,ala(2)
Enkephalinamide-met,ala(2)
Tyr-D-Ala-Gly-Phe-Met-NH2
Dalamid
Dalamide
2-Ala-met-enkephalinamide
Enkephalinamide-met,alanine(2)
[D-Ala2]-methionine enkephalinamide
H-Tyr-D-Ala-Gly-Phe-Met-NH2
Enkephalin, Amide-[D-Ala2, Met5]
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