Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate

Modify Date: 2024-01-03 08:34:12

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate structure
Common Name Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
CAS Number 61260-15-9 Molecular Weight 242.165
Density 1.35 Boiling Point 402.0±45.0 °C at 760 mmHg
Molecular Formula C10H11O5P Melting Point 97-99 ºC
MSDS N/A Flash Point 210.4±49.1 °C

 Names

Name 3-dimethoxyphosphoryl-3H-2-benzofuran-1-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.35
Boiling Point 402.0±45.0 °C at 760 mmHg
Melting Point 97-99 ºC
Molecular Formula C10H11O5P
Molecular Weight 242.165
Flash Point 210.4±49.1 °C
Exact Mass 242.034409
PSA 71.64000
LogP -0.22
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.530
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2932209090

 Synthetic Route

~96%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: KUDOS PHARMACEUTICALS LIMITED Patent: WO2006/21801 A1, 2006 ; Location in patent: Page/Page column 43 ; WO 2006/021801 A1

~96%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: KUDOS PHARMACEUTICALS LIMITED; MAYBRIDGE LIMITED Patent: WO2004/80976 A1, 2004 ; Location in patent: Page 46 ; WO 2004/080976 A1

~90%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: GLOBAL BLOOD THERAPEUTICS, INC.; CYTOKINETICS, INC.; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; METCALF, Brian; CHUANG, Chihyuan; WARRINGTON, Jeffrey; PAULVANNAN, Kumar; JACOBSON, Matthew P.; HUA, Lan; MORGAN, Bradley Patent: WO2013/102142 A1, 2013 ; Location in patent: Paragraph 0166 ;

~89%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: Menear, Keith A.; Adcock, Claire; Boulter, Robert; Cockcroft, Xiao-Ling; Copsey, Louise; Cranston, Aaron; Dillon, Krystyna J.; Drzewiecki, Jan; Garman, Sheila; Gomez, Sylvie; Javaid, Hashim; Kerrigan, Frank; Knights, Charlotte; Lau, Alan; Loh Jr., Vincent M.; Matthews, Ian T. W.; Moore, Stephen; O'Connor, Mark J.; Smith, Graeme C. M.; Martin, Niall M. B. Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6581 - 6591

~%

Detail
Literature: KuDOS Pharmaceuticals Limited Patent: US2002/183325 A1, 2002 ; US 20020183325 A1

~0%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: Kudos Pharmaceuticals Limited; Maybridge Limited Patent: US2005/59663 A1, 2005 ; US 20050059663 A1

~%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: Watanabe; Ijichi; Furukawa Synthesis, 1993 , # 1 p. 94 - 98

~%

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate Structure

Dimethyl (3-oxo...

CAS#:61260-15-9

Literature: Watanabe; Ijichi; Furukawa Synthesis, 1993 , # 1 p. 94 - 98

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

dimethyl phthalide-3-phosphonate
3-dimethoxyphosphoryl-3H-isobenzofuran-1-one
(3-oxo-1,3-dihydro-isobenzofuran-1-yl) phosphonic acid dimethyl ester
dimethyl 3-oxo-1,3-dihydro-2-benzofuran-1-ylphosphonate
Phosphonic acid, P-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-, dimethyl ester
dimethyl 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonate
Dimethyl (3-oxo-1,3-dihydro-2-benzofuran-1-yl)phosphonate
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
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