2-Hydroxycinnamic acid

Modify Date: 2024-01-09 11:46:49

2-Hydroxycinnamic acid structure	Common Name	2-Hydroxycinnamic acid
	CAS Number	614-60-8	Molecular Weight	164.158
	Density	1.3±0.1 g/cm3	Boiling Point	348.0±17.0 °C at 760 mmHg
	Molecular Formula	C₉H₈O₃	Melting Point	217ºC
	MSDS	Chinese USA	Flash Point	178.5±17.4 °C
	Symbol	GHS06	Signal Word	Danger

Use of 2-Hydroxycinnamic acid

2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM[2]

Name	2-Hydroxy Cinnamic Acid
Synonym	More Synonyms

Description	2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM[2]
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	HIV
References	[1]. Tran Minh Ngoc, et al. A new coumarin and cytotoxic activities of constituents from Cinnamomum cassia. Nat Prod Commun. 2014 Apr;9(4):487-8. [2]. Min Zhuang, et al. Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Antiviral Res. 2009 Apr;82(1):73-81.

Density	1.3±0.1 g/cm3
Boiling Point	348.0±17.0 °C at 760 mmHg
Melting Point	217ºC
Molecular Formula	C₉H₈O₃
Molecular Weight	164.158
Flash Point	178.5±17.4 °C
Exact Mass	164.047348
PSA	57.53000
LogP	2.43
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.660

2-Hydroxycinnamic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD9090000

CHEMICAL NAME :: Cinnamic acid, o-hydroxy-, (E)-

CAS REGISTRY NUMBER :: 614-60-8

BEILSTEIN REFERENCE NO. :: 1100900

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H8-O3

MOLECULAR WEIGHT :: 164.17

WISWESSER LINE NOTATION :: QV1U1R BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02587

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H315-H319-H335
Precautionary Statements	P261-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi:Irritant;Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S24/25-S36
RIDADR	UN 2811
WGK Germany	3
RTECS	GD9090000

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(2E)-3-(2-Hydroxyphenyl)-2-propenoic acid

(2E)-3-(2-Hydroxyphenyl)acrylic acid

(E)-o-coumaric acid

trans-2-coumaric acid

o-Coumaric acid

(E)-3-(2-Hydroxyphenyl)-2-propenoic acid

Cinnamic acid, o-hydroxy-, (E)-

Coumaric acid

2-Propenoic acid, 3-(2-hydroxyphenyl)-, (E)-

o-Hydroxy-trans-cinnamic acid

2-Hydroxycinnamic acid, (E)-

QV1U1R BQ &&E or trans Form

(E)-3-(2-Hydroxyphenyl)acrylic acid

Cinnamic acid, o-hydroxy-

2-Propenoic acid, 3-(2-hydroxyphenyl)-, (2E)-

(2E)-3-(2-Hydroxyphenyl)prop-2-enoic acid

EINECS 210-386-4

trans-2-Hydroxycinnamic acid

trans-o-Coumaric Acid

trans-o-Hydroxycinnamic acid

o-Hydroxycinnamic acid

2-Hydroxycinnamic acid

(E)-2-Hydroxycinnamic acid

(E)-o-Hydroxycinnamic acid

(E)-3-(2-Hydroxyphenyl)prop-2-enoic acid

MFCD00004379

ortho-Hydroxycinnamic acid

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Hydroxycinnamic acid
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China
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Hydroxycinnamic acid
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DC Chemicals Limited
China
Product Name: 2-Hydroxycinnamic acid
Price: ￥Inquiry/1g
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Hydroxycinnamic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
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Price: ￥550/10 mM * 1 mL in DMSO

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2-Hydroxycinnamic acid

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