4-Methylumbelliferyl β-D-galactoside

Modify Date: 2024-01-02 12:51:57

4-Methylumbelliferyl β-D-galactoside Structure
4-Methylumbelliferyl β-D-galactoside structure
Common Name 4-Methylumbelliferyl β-D-galactoside
CAS Number 6160-78-7 Molecular Weight 338.309
Density 1.5±0.1 g/cm3 Boiling Point 626.9±55.0 °C at 760 mmHg
Molecular Formula C16H18O8 Melting Point 258-263ºC (dec.)
MSDS USA Flash Point 233.9±25.0 °C

 Use of 4-Methylumbelliferyl β-D-galactoside


4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer[1].

 Names

Name 4-Methylumbelliferyl-beta-D-galactopyranoside
Synonym More Synonyms

 4-Methylumbelliferyl β-D-galactoside Biological Activity

Description 4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer[1].
Related Catalog
References

[1]. Berg JD, et al. Rapid detection of total and fecal coliforms in water by enzymatic hydrolysis of 4-methylumbelliferone-beta-D-galactoside. Appl Environ Microbiol. 1988 Aug;54(8):2118-22.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 626.9±55.0 °C at 760 mmHg
Melting Point 258-263ºC (dec.)
Molecular Formula C16H18O8
Molecular Weight 338.309
Flash Point 233.9±25.0 °C
Exact Mass 338.100159
PSA 129.59000
LogP -0.46
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.641

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R26/27/28
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~93%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Organic and Biomolecular Chemistry, , vol. 4, # 24 p. 4453 - 4459

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4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8271 - 8277

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8271 - 8277

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Collection of Czechoslovak Chemical Communications, , vol. 24, p. 1099,1102

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4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Molecular Pharmacology, , vol. 79, # 3 p. 472 - 478

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 Synonyms

2H-1-Benzopyran-2-one, 7-(β-D-galactopyranosyloxy)-4-methyl-
4-Methylumbelliferyl β-D-galactoside
4-Methyl-2-oxo-2H-chromen-7-yl β-D-galactopyranoside
EINECS 228-185-5
4-methyl-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
MFCD00036773
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