OMDM-1

Modify Date: 2024-01-10 19:35:25

Use of OMDM-1

OMDM-1 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 2.4 μM[1].

Name	omdm-1
Synonym	More Synonyms

Description	OMDM-1 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 2.4 μM[1].
Related Catalog	Research Areas >> Neurological Disease
Target	Ki: 2.4 μM (anandamide cellular uptake)[1]
In Vitro	OMDM-1 shows poor affinity for either CB1 (Ki=12.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively; OMDM-1 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50≥10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1].
References	[1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.

HS Code	2924299090

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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