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616884-62-9

616884-62-9 structure
616884-62-9 structure
  • Name: OMDM-1
  • Chemical Name: omdm-1
  • CAS Number: 616884-62-9
  • Molecular Formula: C27H45NO3
  • Molecular Weight: 431.651
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2016-12-15 10:30:50
  • Modify Date: 2024-01-10 19:35:25
  • OMDM-1 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 2.4 μM[1].

Name omdm-1
Synonyms (9Z)-N-[(2S)-1-Hydroxy-3-(4-hydroxyphenyl)-2-propanyl]-9-octadecenamide
9-Octadecenamide, N-[(1S)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, (9Z)-
Description OMDM-1 is a potent, selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a Ki of 2.4 μM[1].
Related Catalog
Target

Ki: 2.4 μM (anandamide cellular uptake)[1]

In Vitro OMDM-1 shows poor affinity for either CB1 (Ki=12.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively; OMDM-1 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50≥10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1].
References

[1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.

Density 1.0±0.1 g/cm3
Boiling Point 625.8±55.0 °C at 760 mmHg
Molecular Formula C27H45NO3
Molecular Weight 431.651
Flash Point 332.3±31.5 °C
Exact Mass 431.339935
PSA 69.56000
LogP 7.76
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.518
HS Code 2924299090
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%