Heliotrine N-oxide

Modify Date: 2024-01-02 18:55:51

Heliotrine N-oxide Structure
Heliotrine N-oxide structure
Common Name Heliotrine N-oxide
CAS Number 6209-65-0 Molecular Weight 329.38900
Density N/A Boiling Point N/A
Molecular Formula C16H27NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Heliotrine N-oxide


Heliotrine N-oxide is the corresponding PA (pyrrolizidine alkaloid) N-oxide of Heliotrine (HY-126128). Heliotrine N-oxide leads to the formation of pyrrolic DNA adducts and potential initiation of PA-induced liver tumors in vivo[1].

 Names

Name heliotrine N-oxide
Synonym More Synonyms

 Heliotrine N-oxide Biological Activity

Description Heliotrine N-oxide is the corresponding PA (pyrrolizidine alkaloid) N-oxide of Heliotrine (HY-126128). Heliotrine N-oxide leads to the formation of pyrrolic DNA adducts and potential initiation of PA-induced liver tumors in vivo[1].
Related Catalog
In Vitro DNA adduct is a segment of DNA bound to a cancer-causing chemical. This process could be the start of a cancerous cell, or carcinogenesis.
References

[1]. Xiaobo He, et al. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25(4):984-991.

 Chemical & Physical Properties

Molecular Formula C16H27NO6
Molecular Weight 329.38900
Exact Mass 329.18400
PSA 105.42000
LogP 0.29820

 Synonyms

(2S,3R)-2-hydroxy-2-isopropyl-3-methoxy-butyric acid-((7aR)-7c-hydroxy-4-oxy-(4ξ,7ar)-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester)
(2S,3R)-2-Hydroxy-2-isopropyl-3-methoxy-buttersaeure-((7aR)-7c-hydroxy-4-oxy-(4ξ,7ar)-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethylester)
[(7S,8S)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl2-hydroxy-2-(1-methoxyethyl)-3-methylbutanoate