2-Amino-2-(4-chlorophenyl)acetic acid

Modify Date: 2024-01-02 18:45:39

2-Amino-2-(4-chlorophenyl)acetic acid Structure
2-Amino-2-(4-chlorophenyl)acetic acid structure
 Common Name 2-Amino-2-(4-chlorophenyl)acetic acid
CAS Number 6212-33-5 Molecular Weight 185.608
Density 1.4±0.1 g/cm3 Boiling Point 328.8±32.0 °C at 760 mmHg
Molecular Formula C8H8ClNO2 Melting Point 220-230°C
MSDS Chinese USA Flash Point 152.7±25.1 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of 2-Amino-2-(4-chlorophenyl)acetic acid


2-Amino-2-(4-chlorophenyl)acetic acid is a Glycine (HY-Y0966) derivative[1].

 Names

Name DL-4-Chlorophenylglycine
Synonym More Synonyms

 2-Amino-2-(4-chlorophenyl)acetic acid Biological Activity

Description 2-Amino-2-(4-chlorophenyl)acetic acid is a Glycine (HY-Y0966) derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 328.8±32.0 °C at 760 mmHg
Melting Point 220-230°C
Molecular Formula C8H8ClNO2
Molecular Weight 185.608
Flash Point 152.7±25.1 °C
Exact Mass 185.024353
PSA 63.32000
LogP 1.54
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.603

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922499990

 Synthetic Route

2-(4-chlorophenyl)-2-(hydroxyimino)acetic acid structure

2-(4-chlorophen...

CAS#:1353886-52-8

~92%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Liu, Shouxin; Yang, Yihua; Zhen, Xiaoli; Li, Junzhang; He, Huimin; Feng, Juan; Whiting, Andrew Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 663 - 670
(4-Chlorophenyl)(oxo)acetic acid structure

(4-Chlorophenyl...

CAS#:7099-88-9

~90%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Talwar, Dinesh; Salguero, Noemi Poyatos; Robertson, Craig M.; Xiao, Jianliang Chemistry - A European Journal, 2014 , vol. 20, # 1 p. 245 - 252
5-(4-chlorophenyl)imidazolidine-2,4-dione structure

5-(4-chlorophen...

CAS#:6212-32-4

~70%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Pinna, G. A.; Gavini, E.; Cignarella, G.; Scolastico, S.; Fadda, P. European Journal of Medicinal Chemistry, 1995 , vol. 30, # 6 p. 515 - 520
Methyl (2-bromo-4-chlorophenyl)acetate structure

Methyl (2-bromo...

CAS#:24091-92-7

~%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Journal of Organic Chemistry, , vol. 56, # 1 p. 420 - 423
1-chloro-4-(isocyanomethyl)benzene structure

1-chloro-4-(iso...

CAS#:39546-47-9

~%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Journal of Organic Chemistry, , vol. 38, p. 2094 - 2096
4-Chlorobenzaldehyde structure

4-Chlorobenzaldehyde

CAS#:104-88-1

~%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: European Journal of Medicinal Chemistry, , vol. 30, # 6 p. 515 - 520
α-Isocyano-p-chlorphenylessigsaeureaethylester structure

α-Isocyano-p-ch...

CAS#:39533-35-2

~%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Journal of Organic Chemistry, , vol. 38, p. 2094 - 2096
4-Chlorobenzyl cyanide structure

4-Chlorobenzyl ...

CAS#:140-53-4

~%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Journal of Organic Chemistry, , vol. 31, p. 3708 - 3711
H-D-Phg(4-Cl)-OH structure

H-D-Phg(4-Cl)-OH

CAS#:43189-37-3

~%

2-Amino-2-(4-chlorophenyl)acetic acid Structure

2-Amino-2-(4-ch...

CAS#:6212-33-5

Literature: Journal of Organic Chemistry, , vol. 48, # 5 p. 627 - 634

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

Benzeneacetic acid, α-amino-4-chloro-
4-CHLOROPHENYL GLYCINE
P-CHLORO PHENYL GLYCINE
Amino(4-chlorophenyl)acetic acid
chlorophenylglycine
RARECHEM AK ML 0510
DL-4-Chlorophenylgly
DL-4-Cl-Phg-OH
PCPG
MFCD00049328
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