Quinfamide

Modify Date: 2024-01-20 15:45:12

Quinfamide Structure
Quinfamide structure
 Common Name Quinfamide
CAS Number 62265-68-3 Molecular Weight 354.18
Density 1.428g/cm3 Boiling Point 551.3ºC at 760mmHg
Molecular Formula C16H13Cl2NO4 Melting Point 145-146ºC
MSDS N/A Flash Point 287.2ºC

 Use of Quinfamide


Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1].

 Names

Name [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate
Synonym More Synonyms

 Quinfamide Biological Activity

Description Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1].
Related Catalog
References

[1]. Davila-Gutierrez CE, et al. Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children. Am J Trop Med Hyg. 2002 Mar;66(3):251-4.

 Chemical & Physical Properties

Density 1.428g/cm3
Boiling Point 551.3ºC at 760mmHg
Melting Point 145-146ºC
Molecular Formula C16H13Cl2NO4
Molecular Weight 354.18
Flash Point 287.2ºC
Exact Mass 353.02200
PSA 59.75000
LogP 3.64670
Index of Refraction 1.599
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LU0215000
CHEMICAL NAME :
2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
CAS REGISTRY NUMBER :
62265-68-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C16-H13-Cl2-N-O4
MOLECULAR WEIGHT :
354.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979

 Safety Information

HS Code 2934999090

 Synthetic Route

2-Furoyl chloride structure

2-Furoyl chloride

CAS#:527-69-5

1-(Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinol structure

1-(Dichloroacet...

CAS#:62265-67-2

Carbon structure

Carbon

CAS#:7440-44-0

~%

Quinfamide Structure

Quinfamide

CAS#:62265-68-3

Literature: US3997542 A1, ;

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-(dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl 2-furoate
Quinfamido [INN-Spanish]
Quinfamide
Quinfamidum [INN-Latin]
1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline
EINECS 263-478-1
Amenide
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Chemsrc provides Quinfamide(CAS#:62265-68-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Quinfamide are included as well.>> amp version: Quinfamide

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