Zabofloxacin hydrochloride

Modify Date: 2024-02-24 10:25:08

Zabofloxacin hydrochloride Structure
Zabofloxacin hydrochloride structure
Common Name Zabofloxacin hydrochloride
CAS Number 623574-00-5 Molecular Weight 437.85300
Density N/A Boiling Point N/A
Molecular Formula C19H21ClFN5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zabofloxacin hydrochloride


Zabofloxacin hydrochloride (DW-224a) is a novel fluoronaphthyridone quinolone that is considered a potent antibacterial candidate for clinical trials.Zabofloxacin hydrochloride (DW-224a) has excellent activity against gram-positive pathogens including Steptococcus aureus (S. aureus), Streptococcus pyogenes (S. pyrigenes), and S. pneumonia.Zabofloxacin hydrochloride (DW-224a) is considered as an alternative candidate for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1].

 Names

Name 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diazaspiro[3.4]octan-6-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid,hydrochloride
Synonym More Synonyms

 Zabofloxacin hydrochloride Biological Activity

Description Zabofloxacin hydrochloride (DW-224a) is a novel fluoronaphthyridone quinolone that is considered a potent antibacterial candidate for clinical trials.Zabofloxacin hydrochloride (DW-224a) has excellent activity against gram-positive pathogens including Steptococcus aureus (S. aureus), Streptococcus pyogenes (S. pyrigenes), and S. pneumonia.Zabofloxacin hydrochloride (DW-224a) is considered as an alternative candidate for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1].
Related Catalog
References

[1]. Park HS, et al. Antimicrobial Activity of Zabofloxacin against Clinically Isolated Streptococcus pneumoniae. Molecules. 2016 Nov 17;21(11). pii: E1562.

 Chemical & Physical Properties

Molecular Formula C19H21ClFN5O4
Molecular Weight 437.85300
Exact Mass 437.12700
PSA 109.05000
LogP 2.17650

 Synonyms

1,8-Naphthyridine-3-carboxylic acid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-(methoxyimino)-2,6-diazaspiro(3.4)oct-6-yl)-4-oxo-,hydrochloride (1:1)
DW-224a
Zabofloxacin hydrochloride
1,8-Naphthyridine-3-carboxylic acid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-(methoxyimino)-2,6-diazaspiro(3.4)oct-6-yl)-4-oxo-,monohydrochloride
Zabofloxacin monohydrochloride
UNII-O889MR47PQ
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