4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one

Modify Date: 2024-01-06 12:40:17

4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one Structure
4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one structure
Common Name 4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one
CAS Number 62499-71-2 Molecular Weight 356.412
Density 1.2±0.1 g/cm3 Boiling Point 505.2±50.0 °C at 760 mmHg
Molecular Formula C21H24O5 Melting Point N/A
MSDS N/A Flash Point 220.7±30.2 °C

 Use of 4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one


Isodihydrofutoquinol B (compound 9), an active compound, can be isolated from the stems of Piper kadsura (Choisy) Ohwi. Isodihydrofutoquinol B has A neuroprotective effect on Aβ25-35-induced PC12 cell damage with E50 values of 3.06-29.3μM[1].

 Names

Name (S)-2-allyl-4-((R)-1-(benzo[d][1,3]dioxol-5-yl)propan-2-yl)-4,5-dimethoxycyclohexa-2,5-dien-1-one
Synonym More Synonyms

  Biological Activity

Description Isodihydrofutoquinol B (compound 9), an active compound, can be isolated from the stems of Piper kadsura (Choisy) Ohwi. Isodihydrofutoquinol B has A neuroprotective effect on Aβ25-35-induced PC12 cell damage with E50 values of 3.06-29.3μM[1].
Related Catalog
References

[1]. Chen H, et al. Neolignans and amide alkaloids from the stems of Piper kadsura and their neuroprotective activity. Phytochemistry. 2022 Nov;203:113336.  

[2]. Prasad A K, et al. Lignans and neolignans from stems and fruits of Piper wightii[J]. Tetrahedron, 1994, 50(7): 2231-2240.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 505.2±50.0 °C at 760 mmHg
Molecular Formula C21H24O5
Molecular Weight 356.412
Flash Point 220.7±30.2 °C
Exact Mass 356.162384
PSA 53.99000
LogP 4.46
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.567

 Safety Information

Hazard Codes Xi

 Synonyms

2,5-Cyclohexadien-1-one, 4-[2-(1,3-benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propen-1-yl)-
2-Allyl-4-[1-(1,3-benzodioxol-5-yl)-2-propanyl]-4,5-dimethoxy-2,5-cyclohexadien-1-one
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