SIB 1893

Modify Date: 2024-01-07 21:32:01

SIB 1893 Structure
SIB 1893 structure
Common Name SIB 1893
CAS Number 6266-99-5 Molecular Weight 195.26000
Density 1.072g/cm3 Boiling Point 307.3ºC at 760mmHg
Molecular Formula C14H13N Melting Point N/A
MSDS N/A Flash Point 128.8ºC

 Use of SIB 1893


(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist[1].

 Names

Name SIB 1893,2-Methyl-6-(2-phenylethenyl)pyridine

 SIB 1893 Biological Activity

Description (E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist[1].
Related Catalog
In Vivo (E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner[1].
References

[1]. Łuszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801.

 Chemical & Physical Properties

Density 1.072g/cm3
Boiling Point 307.3ºC at 760mmHg
Molecular Formula C14H13N
Molecular Weight 195.26000
Flash Point 128.8ºC
Exact Mass 195.10500
PSA 12.89000
LogP 3.56040
Index of Refraction 1.651

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
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