N-Ethylformamide

Modify Date: 2024-01-06 13:20:27

N-Ethylformamide Structure
N-Ethylformamide structure
Common Name N-Ethylformamide
CAS Number 627-45-2 Molecular Weight 73.09380
Density 0.950 g/mL at 20ºC(lit.) Boiling Point 202-204ºC
Molecular Formula C3H7NO Melting Point -60.43°C (estimate)
MSDS Chinese USA Flash Point 67ºC

 Names

Name n-ethylformamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.950 g/mL at 20ºC(lit.)
Boiling Point 202-204ºC
Melting Point -60.43°C (estimate)
Molecular Formula C3H7NO
Molecular Weight 73.09380
Flash Point 67ºC
Exact Mass 73.05280
PSA 29.10000
LogP 0.77910
Index of Refraction n20/D 1.432

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ2725000
CHEMICAL NAME :
Formamide, N-ethyl-
CAS REGISTRY NUMBER :
627-45-2
BEILSTEIN REFERENCE NO. :
1737860
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C3-H7-N-O
MOLECULAR WEIGHT :
73.11
WISWESSER LINE NOTATION :
VHM2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,645,1968
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 27,873,1972

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xi
Safety Phrases S23-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LQ2725000
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles6

More Articles
N-methylformamide: antitumour activity and metabolism in mice.

Br. J. Cancer 45(6) , 843-50, (1982)

The antitumour activities of N-methylformamide, N-ethylformamide and formamide against a number of murine tumours in vivo (Sarcoma 180, M5076 ovarian sarcoma and TLX5 lymphoma) have been estimated. In...

Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: detection of genotoxicity of N-alkylformamides.

Environ. Mol. Mutagen. 36(2) , 97-104, (2000)

A cDNA coding for rat cytochrome P450 2E1 was cloned into the multicopy vector pYeDP60 and expressed in haploid RSY6 and diploid RS112 yeast strains of Saccharomyces cerevisiae under control of the GA...

An investigation of the relationship between the hepatotoxicity and the metabolism of N-alkylformamides.

J. Pharmacol. Exp. Ther. 240(1) , 265-70, (1987)

The hepatotoxicity and metabolism of the following close analogs of the hepatotoxic antitumor agent N-methylformamide (NMF) were investigated in CBA/CA mice: N-ethylformamide (NEF), dimethylformamide ...

 Synonyms

EINECS 211-001-2
N-formylethylamine
monoethyl-formamide
Ethylformamide
MFCD00042672
N-ethyl carboxamide
N-ethyl-formamide
Formamide,N-ethyl
N-Aethylformamid [German]
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