KM-233

Modify Date: 2024-01-08 12:52:35

KM-233 Structure
KM-233 structure
Common Name KM-233
CAS Number 628263-22-9 Molecular Weight 362.50
Density 1.1±0.1 g/cm3 Boiling Point 436.8±45.0 °C at 760 mmHg
Molecular Formula C25H30O2 Melting Point N/A
MSDS N/A Flash Point 171.9±23.0 °C

 Use of KM-233


KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research[1].

 Names

Name 6,6,9-trimethyl-3-(2-phenylpropan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
Synonym More Synonyms

 KM-233 Biological Activity

Description KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research[1].
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References

[1]. Duntsch C, et al. Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. J Neurooncol. 2006 Apr;77(2):143-52.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 436.8±45.0 °C at 760 mmHg
Molecular Formula C25H30O2
Molecular Weight 362.50
Flash Point 171.9±23.0 °C
Exact Mass 362.224579
PSA 29.46000
LogP 7.63
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.560

 Synonyms

KM-233
6H-Dibenzo[b,d]pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-(1-methyl-1-phenylethyl)-, (6aR,10aR)-
(6aR,10aR)-6,6,9-Trimethyl-3-(2-phenyl-2-propanyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
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