(±)-threo-3-Methylglutamic acid
Modify Date: 2024-01-03 12:33:24
(±)-threo-3-Methylglutamic acid structure
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Common Name | (±)-threo-3-Methylglutamic acid | ||
|---|---|---|---|---|
| CAS Number | 63088-04-0 | Molecular Weight | 161.15600 | |
| Density | 1.329g/cm3 | Boiling Point | 329.4ºC at 760 mmHg | |
| Molecular Formula | C6H11NO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 153ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of (±)-threo-3-Methylglutamic acid(±)-threo-3-Methylglutamic acid is a potent EAAT2/4 inhibitor. (±)-threo-3-Methylglutamic acid also is an ionotropic glutamate receptor agonist. (±)-threo-3-Methylglutamic acid inhibits glutamate uptake by rod outer segments[1][2]. |
| Name | (+/-)-threo-3-Methylglutamic Acid |
|---|---|
| Synonym | More Synonyms |
| Description | (±)-threo-3-Methylglutamic acid is a potent EAAT2/4 inhibitor. (±)-threo-3-Methylglutamic acid also is an ionotropic glutamate receptor agonist. (±)-threo-3-Methylglutamic acid inhibits glutamate uptake by rod outer segments[1][2]. |
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| Related Catalog | |
| In Vitro | (±)-threo-3-Methylglutamic acid (0-300 µM) 以浓度依赖性方式抑制视杆外节对谷氨酸的摄取，IC50 值为 38.35 µM[2]。 |
| References |
| Density | 1.329g/cm3 |
|---|---|
| Boiling Point | 329.4ºC at 760 mmHg |
| Molecular Formula | C6H11NO4 |
| Molecular Weight | 161.15600 |
| Flash Point | 153ºC |
| Exact Mass | 161.06900 |
| PSA | 100.62000 |
| LogP | 0.20940 |
| Appearance of Characters | white to off-white |
| Index of Refraction | 1.512 |
| Storage condition | Store at RT |
| Water Solubility | H2O: >1.5mg/dL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2922499990 |
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Guide to Receptors and Channels (GRAC), 4th Edition.
Br. J. Pharmacol. 158 Suppl 1 , S1-254, (2009)
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In vitro comparison of the effect of inhalation delay and flow rate on the emitted dose from three valved holding chambers.
J. Aerosol Med. Pulm. Drug Deliv. 27 Suppl 1 , S37-43, (2014) Valved holding chambers (VHCs) are accessory devices for pressurized metered dose inhalers (pMDIs). Use of a VHC may help overcome coordination issues associated with drug delivery via the pMDI alone.... |
| (±)-threo-3-Methylglutamic acid |