Sennidin A

Modify Date: 2024-01-02 13:04:24

Sennidin A Structure
Sennidin A structure
Common Name Sennidin A
CAS Number 641-12-3 Molecular Weight 538.458
Density 1.7±0.1 g/cm3 Boiling Point 801.8±65.0 °C at 760 mmHg
Molecular Formula C30H18O10 Melting Point N/A
MSDS N/A Flash Point 452.6±30.8 °C

 Use of Sennidin A


Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation[1][2].

 Names

Name sennidine a
Synonym More Synonyms

 Sennidin A Biological Activity

Description Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation[1][2].
Related Catalog
References

[1]. Furuta A, et al. Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase. Int J Mol Sci. 2015 Aug 7;16(8):18439-53.

[2]. Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes. Life Sciences. 2006.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 801.8±65.0 °C at 760 mmHg
Molecular Formula C30H18O10
Molecular Weight 538.458
Flash Point 452.6±30.8 °C
Exact Mass 538.090027
PSA 189.66000
LogP 8.24
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.806
Storage condition 2-8℃

 Safety Information

Risk Phrases 22
Safety Phrases 22-45

 Synonyms

SENECIONINE(SH)
1',1,8',8-Tetrahydroxy-10,10'-dihydroanthrone-3,3'-dicarboxylic acid
EINECS 211-371-5
dihydroxydianthrone
(+)-4,5,4',5'-tetrahydroxy-10,10'-dioxo-9,10,9',10'-tetrahydro-[9,9']bianthryl-2,2'-dicarboxylic acid
4,4',5,5'-Tetrahydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
(R*,R*)-(+)-9,9',10,10'-Tetrahydro-4,4',5,5'-tetrahydroxy-10,10'-dioxo(9,9'-bianthracene)-2,2'-dicarboxylic acid
[9,9'-Bianthracene]-2,2'-dicarboxylic acid, 9,9',10,10'-tetrahydro-4,4',5,5'-tetrahydroxy-10,10'-dioxo-
Sennidin A
(+)-4,5,4',5'-Tetrahydroxy-10,10'-dioxo-9,10,9',10'-tetrahydro-[9,9']bianthryl-2,2'-dicarbonsaeure
(+)-4.5.4'.5'-Tetrahydroxy-10.10'-dioxo-9.10.9'.10'-tetrahydro-[9.9']bianthryl-dicarbonsaeure-(2.2')
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