Moclobemide N-Oxide

Modify Date: 2024-01-15 09:54:51

Moclobemide N-Oxide Structure
Moclobemide N-Oxide structure
Common Name Moclobemide N-Oxide
CAS Number 64544-24-7 Molecular Weight 284.74
Density N/A Boiling Point N/A
Molecular Formula C13H17ClN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Moclobemide N-Oxide


Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. Moclobemide N-Oxide retains certain MAO-A (monoamine oxidase) inhibitory activity, but is generally present in low concentrations. Moclobemide N-Oxide can be detected by UV absorption at 240 nm[1][2].

 Names

Name Moclobemide N-Oxide
Synonym More Synonyms

 Moclobemide N-Oxide Biological Activity

Description Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. Moclobemide N-Oxide retains certain MAO-A (monoamine oxidase) inhibitory activity, but is generally present in low concentrations. Moclobemide N-Oxide can be detected by UV absorption at 240 nm[1][2].
Related Catalog
Target

MAO-A

References

[1]. Rakic Ignjatovic A, et al. Moclobemide monotherapy vs. combined therapy with valproic acid or carbamazepine in depressive patients: a pharmacokinetic interaction study. Br J Clin Pharmacol. 2009 Feb;67(2):199-208.

[2]. Geschke R, et al. Determination of the new monoamine oxidase inhibitor moclobemide and three of its metabolites in biological fluids by high-performance liquid chromatography. J Chromatogr. 1987 Sep 4;420(1):111-20.

 Chemical & Physical Properties

Molecular Formula C13H17ClN2O3
Molecular Weight 284.74
Exact Mass 284.092773
LogP -0.10

 Synonyms

Ro 12-5637
4-Chloro-N-[2-(4-oxido-4-morpholinyl)ethyl]benzamide
Benzamide, 4-chloro-N-[2-(4-oxido-4-morpholinyl)ethyl]-
4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide N-Oxide
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