Gallamine triethiodide structure
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Common Name | Gallamine triethiodide | ||
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CAS Number | 65-29-2 | Molecular Weight | 891.529 | |
Density | 0.983g/cm3 | Boiling Point | 502.6ºC at 760 mmHg | |
Molecular Formula | C30H60I3N3O3 | Melting Point | 235ºC (dec.) | |
MSDS | Chinese USA | Flash Point | 125.9ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Gallamine triethiodideGallamine Triethiodide is a synthetic nondepolarizing blocking drug.Target: mAChRGallamine triethiodide is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Gallamine triethiodide is commonly used to stabilize muscle contractions during surgical procedures. From Wikipedia. |
Name | Gallamine triethiodide |
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Synonym | More Synonyms |
Description | Gallamine Triethiodide is a synthetic nondepolarizing blocking drug.Target: mAChRGallamine triethiodide is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Gallamine triethiodide is commonly used to stabilize muscle contractions during surgical procedures. From Wikipedia. |
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Related Catalog | |
References |
Density | 0.983g/cm3 |
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Boiling Point | 502.6ºC at 760 mmHg |
Melting Point | 235ºC (dec.) |
Molecular Formula | C30H60I3N3O3 |
Molecular Weight | 891.529 |
Flash Point | 125.9ºC |
Exact Mass | 891.176819 |
PSA | 27.69000 |
Index of Refraction | 1.501 |
Storage condition | 2-8°C |
Water Solubility | H2O: 100 mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H315-H319-H335 |
Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful; |
Risk Phrases | R22;R36/37/38 |
Safety Phrases | S26-S36-S45 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | BS1100000 |
~% Gallamine triet... CAS#:65-29-2 |
Literature: Annales Pharmaceutiques Francaises, , vol. 6, p. 450 |
Precursor 2 | |
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DownStream 0 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
J. Sci. Ind. Res. 65(10) , 808, (2006) Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ... |
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Developing structure-activity relationships for the prediction of hepatotoxicity.
Chem. Res. Toxicol. 23 , 1215-22, (2010) Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ... |
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A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug Metab. Dispos. 38 , 2302-8, (2010) Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti... |
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MFCD00011832 |
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EINECS 200-605-1 |
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