Ac-Arg-Gly-Lys-AMC trifluoroacetate salt

Modify Date: 2024-01-09 22:23:28

Ac-Arg-Gly-Lys-AMC trifluoroacetate salt Structure
Ac-Arg-Gly-Lys-AMC trifluoroacetate salt structure
Common Name Ac-Arg-Gly-Lys-AMC trifluoroacetate salt
CAS Number 660846-99-1 Molecular Weight 558.63
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C26H38N8O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ac-Arg-Gly-Lys-AMC trifluoroacetate salt


Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

 Names

Name N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide
Synonym More Synonyms

 Ac-Arg-Gly-Lys-AMC trifluoroacetate salt Biological Activity

Description Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Related Catalog
References

[1]. Noonepalle S, et, al. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63(18):10246-10262.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C26H38N8O6
Molecular Weight 558.63
Exact Mass 558.291443
LogP -1.07
Index of Refraction 1.640

 Synonyms

L-Lysinamide, N2-acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide
Ac-Arg-Gly-Lys-AMC trifluoroacetate salt
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