Pergolide

Modify Date: 2024-01-08 18:25:27

Pergolide Structure
Pergolide structure
Common Name Pergolide
CAS Number 66104-22-1 Molecular Weight 314.488
Density 1.1±0.1 g/cm3 Boiling Point 491.3±35.0 °C at 760 mmHg
Molecular Formula C19H26N2S Melting Point 207.5ºC
MSDS N/A Flash Point 250.9±25.9 °C

 Use of Pergolide


Pergolide (LY127809 (free base)) is an ergot-derived orally active dopamine receptor agonist. Pergolide can be used for Parkinson disease research[1].

 Names

Name pergolide
Synonym More Synonyms

 Pergolide Biological Activity

Description Pergolide (LY127809 (free base)) is an ergot-derived orally active dopamine receptor agonist. Pergolide can be used for Parkinson disease research[1].
Related Catalog
References

[1]. Van Camp G, et al. Treatment of Parkinson's disease with pergolide and relation to restrictive valvular heart disease. Lancet. 2004 Apr 10;363(9416):1179-83.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 491.3±35.0 °C at 760 mmHg
Melting Point 207.5ºC
Molecular Formula C19H26N2S
Molecular Weight 314.488
Flash Point 250.9±25.9 °C
Exact Mass 314.181671
PSA 44.33000
LogP 4.49
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.614

 Safety Information

RIDADR UN 1544 6.1/PG II
RTECS KE6344964
Packaging Group II

 Synthetic Route

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Pergolide Structure

Pergolide

CAS#:66104-22-1

Literature: US4782152 A1, ;

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Pergolide Structure

Pergolide

CAS#:66104-22-1

Literature: US4166182 A1, ;

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Pergolide Structure

Pergolide

CAS#:66104-22-1

Literature: Journal of the Chemical Society. Perkin Transactions 1, , # 19 p. 2398 - 2403

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Pergolide Structure

Pergolide

CAS#:66104-22-1

Literature: Anastasia; Cighetti; Allevi Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 19 p. 2398 - 2403

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Pergolide Structure

Pergolide

CAS#:66104-22-1

Literature: Organic Process Research and Development, , vol. 10, # 2 p. 198 - 202

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Pergolide Structure

Pergolide

CAS#:66104-22-1

Literature: Journal of the Chemical Society. Perkin Transactions 1, , # 19 p. 2398 - 2403

 Synonyms

pergolida
(6aR,9R,10aR)-9-[(methylsulfanyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline
Permax (TN)
(8b)-8-[(Methylthio)methyl]-6-propylergoline
Pergolidum [INN-Latin]
(6aR,9R,10aR)-9-(Methylthiomethyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline
D-6-n-Propyl-8b-methylmercaptomethylergoline
Ly 141B
(6aR,9R,10aR)-9-[(Methylsulfanyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]chinolin
8β-[(Methylthio)methyl]-6-propylergoline
Permax
Ergoline, 8-[(methylthio)methyl]-6-propyl-, (8β)-
Pergolide
Pergolidum
Pergolida [INN-Spanish]
(6aR,9R,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline
Ergoline, 8-((methylthio)methyl)-6-propyl-, (8β)-
UNII-24MJ822NZ9
Pergolide (INN)
(8β)-8-[(methylthio)methyl]-6-propylergoline
(8β)-8-[(Methylsulfanyl)methyl]-6-propylergoline
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