NSC47924

Modify Date: 2024-01-14 17:29:38

NSC47924 Structure
NSC47924 structure
Common Name NSC47924
CAS Number 6638-24-0 Molecular Weight 279.33300
Density 1.235g/cm3 Boiling Point 487.8ºC at 760 mmHg
Molecular Formula C18H17NO2 Melting Point N/A
MSDS N/A Flash Point 248.8ºC

 Use of NSC47924


NSC47924 is a laminin receptor (LR) inhibitor. NSC47924 affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. NSC47924 can be used for testing prion diseases[1].

 Names

Name L-N1-benzylhistidine methyl ester dihydrochloride

 NSC47924 Biological Activity

Description NSC47924 is a laminin receptor (LR) inhibitor. NSC47924 affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. NSC47924 can be used for testing prion diseases[1].
Related Catalog
References

[1]. Sarnataro D, et al. The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. Sci Rep. 2016 Apr 13;6:24457.  

 Chemical & Physical Properties

Density 1.235g/cm3
Boiling Point 487.8ºC at 760 mmHg
Molecular Formula C18H17NO2
Molecular Weight 279.33300
Flash Point 248.8ºC
Exact Mass 279.12600
PSA 41.49000
LogP 4.23910
Index of Refraction 1.693

 Synthetic Route

~75%

NSC47924 Structure

NSC47924

CAS#:6638-24-0

Literature: Shaikh, Abdul Kadar; Cobb, Alexander J. A.; Varvounis, George Organic Letters, 2012 , vol. 14, # 4 p. 1183 - 1183

~%

NSC47924 Structure

NSC47924

CAS#:6638-24-0

Literature: Shaikh, Abdul Kadar; Cobb, Alexander J. A.; Varvounis, George Organic Letters, 2012 , vol. 14, # 2 p. 584 - 587

~%

NSC47924 Structure

NSC47924

CAS#:6638-24-0

Literature: Shaikh, Abdul Kadar; Cobb, Alexander J. A.; Varvounis, George Organic Letters, 2012 , vol. 14, # 2 p. 584 - 587

~%

NSC47924 Structure

NSC47924

CAS#:6638-24-0

Literature: Shaikh, Abdul Kadar; Cobb, Alexander J. A.; Varvounis, George Organic Letters, 2012 , vol. 14, # 2 p. 584 - 587

~%

NSC47924 Structure

NSC47924

CAS#:6638-24-0

Literature: Kaupp, Gerd; Schmeyers, Jens; Boy, Juergen Advanced Synthesis and Catalysis, 2000 , vol. 342, # 3 p. 269 - 280

~49%

NSC47924 Structure

NSC47924

CAS#:6638-24-0

Literature: Mohrle; Schake Archiv der Pharmazie, 1992 , vol. 325, # 11 p. 695 - 700
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