Destruxin A
Modify Date: 2024-01-10 18:18:23
Destruxin A structure
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Common Name | Destruxin A | ||
|---|---|---|---|---|
| CAS Number | 6686-70-0 | Molecular Weight | 577.71300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H47N5O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Destruxin ADestruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities[1]. |
| Name | (3S,10S,13S,16S,19R)-16-[(2S)-butan-2-yl]-10,11,14-trimethyl-13-propan-2-yl-3-prop-2-enyl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone |
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| Synonym | More Synonyms |
| Description | Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C29H47N5O7 |
|---|---|
| Molecular Weight | 577.71300 |
| Exact Mass | 577.34800 |
| PSA | 152.41000 |
| LogP | 1.21150 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Risk Phrases | 20/21/22-36/37/38-48 |
| Safety Phrases | 26-36-45 |
| RIDADR | NONH for all modes of transport |
| RTECS | HH1500000 |
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Concurrence of losing a chromosome and the ability to produce destruxins in a mutant of Metarhizium anisopliae.
FEMS Microbiol. Lett. 226(2) , 373-8, (2003) In a previous study, a spontaneous subtilisin pr1A and pr1B gene-deficient mutant of the entomopathogenic fungus Metarhizium anisopliae strain V275 has been identified [Wang, C.-S. et al. (2002) FEMS ... |
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Synthesis and biological evaluation of destruxin A and related analogs.
J. Pept. Res. 58(1) , 1-11, (2001) This report describes the development of an efficient solid-phase synthesis protocol and adaptation of reported solution phase procedures for the synthesis of the cyclic depsihexapeptide destruxin A a... |
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Non-cyclic AMP-dependent, positive inotropic cyclodepsipeptides with negative chronotropy.
J. Pharmacol. Exp. Ther. 290(3) , 1006-12, (1999) The effects of natural cyclodepsipeptides (CDPs) on isolated rat cardiac tissue preparations were examined in vitro. Destruxin A, destruxin B (DB), roseotoxin B (RB), and roseocardin (RC), a novel CDP... |
| Destruxin A from Metarrhizium anisopliae |