For-Met-Leu-Phe-Lys-OH

Modify Date: 2024-01-10 11:13:20

For-Met-Leu-Phe-Lys-OH Structure
For-Met-Leu-Phe-Lys-OH structure
Common Name For-Met-Leu-Phe-Lys-OH
CAS Number 67247-11-4 Molecular Weight 565.73
Density N/A Boiling Point N/A
Molecular Formula C27H43N5O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of For-Met-Leu-Phe-Lys-OH


N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].

 Names

Name N-Formyl-L-methionyl-L-leucyl-L-phenylalanyl-L-lysine
Synonym More Synonyms

 For-Met-Leu-Phe-Lys-OH Biological Activity

Description N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].
Related Catalog
Target

EC50: 3.5 nM (FPR1), 6.7 μM (FPR2), 0.88 μM (FPR2-D2817.32G)[1]

References

[1]. He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306.

 Chemical & Physical Properties

Molecular Formula C27H43N5O6S
Molecular Weight 565.73
Exact Mass 565.29300
PSA 205.02000
LogP 3.71070

 Synonyms

L-Lysine,N-formyl-L-methionyl-L-leucyl-L-phenylalanyl
(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid
FOR-MET-LEU-PHE-LYS-OH
FOR-MET-LEU-PHE-LYS
N-Formyl-Met-Leu-Phe-Lys
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