Vanoxerine dihydrochloride

Modify Date: 2024-01-03 18:18:20

Vanoxerine dihydrochloride Structure
Vanoxerine dihydrochloride structure
Common Name Vanoxerine dihydrochloride
CAS Number 67469-78-7 Molecular Weight 523.485
Density N/A Boiling Point 542.7ºC at 760 mmHg
Molecular Formula C28H34Cl2F2N2O Melting Point 221 °C
MSDS USA Flash Point 282ºC

 Use of Vanoxerine dihydrochloride


Vanoxerine dihydrochloride is a potent and selective dopamine reuptake inhibitor.

 Names

Name vanoxerine dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 542.7ºC at 760 mmHg
Melting Point 221 °C
Molecular Formula C28H34Cl2F2N2O
Molecular Weight 523.485
Flash Point 282ºC
Exact Mass 522.201599
PSA 15.71000
LogP 6.80100

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles29

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Serotonin at the level of the amygdala and orbitofrontal cortex modulates distinct aspects of positive emotion in primates.

Int. J. Neuropsychopharmacol. , 1-15, (2011)

Impaired top-down regulation of the amygdala, and its modulation by serotonin (5-HT), is strongly implicated in the dysregulation of negative emotion that characterizes a number of affective disorders...

Dopamine uptake inhibitors but not dopamine releasers induce greater increases in motor behavior and extracellular dopamine in adolescent rats than in adult male rats.

J. Pharmacol. Exp. Ther. 335(1) , 124-32, (2010)

Most life-long drug addiction begins during adolescence. Important structural and functional changes in brain occur during adolescence and developmental differences in forebrain dopamine systems could...

Differential effects of dopamine transporter inhibitors in the rodent Iowa gambling task: relevance to mania.

Psychopharmacology 225(3) , 661-74, (2013)

The Iowa Gambling Task (IGT) can be used to quantify impulsive and risky choice behaviors in psychiatric patients, e.g., bipolar disorder (BD) sufferers. Although developing treatments for these behav...

 Synonyms

1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine dihydrochloride
Vanoxerine dihydrochloride
Piperazine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)-, hydrochloride (1:2)
MFCD00055193
1-[2-[bis(4-fluorophenyl)methoxy]-ethyl]-4-[3-phenylpropyl]piperazine dihydrochloride
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine,dihydrochloride
Vanoxerine hydrochloride
Vanoxerine (dihydrochloride)
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