GPRP structure
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Common Name | GPRP | ||
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CAS Number | 67869-62-9 | Molecular Weight | 425.48300 | |
Density | 1.55 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C18H31N7O5 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Use of GPRPGPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2]. |
Name | gly-pro-arg-pro |
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Synonym | More Synonyms |
Description | GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2]. |
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Related Catalog | |
References |
Density | 1.55 g/cm3 |
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Molecular Formula | C18H31N7O5 |
Molecular Weight | 425.48300 |
Exact Mass | 425.23900 |
PSA | 194.94000 |
Index of Refraction | 1.691 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Precursor 9 | |
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DownStream 0 |
Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.
J. Thromb. Haemost. 12(8) , 1342-52, (2014) Integrin-linked kinase (ILK) and its associated complex of proteins are involved in many cellular activation processes, including cell adhesion and integrin signaling. We have previously demonstrated ... |
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Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP.
Blood 126 , 873-9, (2015) Immune thrombocytopenia (ITP) patients with similarly low platelet counts differ in their tendency to bleed. To determine if differences in platelet function in ITP patients account for this variation... |
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Procoagulant platelets form an α-granule protein-covered "cap" on their surface that promotes their attachment to aggregates.
J. Biol. Chem. 288(41) , 29621-32, (2013) Strongly activated "coated" platelets are characterized by increased phosphatidylserine (PS) surface expression, α-granule protein retention, and lack of active integrin αIIbβ3. To study how they are ... |
glycine-proline-arginine-proline |
FIBRINOLYSIS INHIBITNG FACTOR |
LAUDANO-DOOLITTLE PEPTIDE |
GPRP FIBRIN ANTIPOLYMERANT |
GPRP |
glycyl-L-prolyl-L-arginyl-L-prolin |
MFCD00133378 |
glycyl-prolyl-arginyl-proline |
FIBRINOLYSIS INHIBITING FACTOR |
M.W. 425.49 C18H31N7O5 |