Berberine chloride hydrate

Modify Date: 2024-01-03 19:13:44

Berberine chloride hydrate structure	Common Name	Berberine chloride hydrate
	CAS Number	68030-18-2	Molecular Weight	389.83000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₀ClNO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Berberine chloride hydrate

Berberine chloride hydrate is an alkaloid in several plants with various biological functions, including insulin-sensitizing, anti-inflammatory, and anti-oxidant activity. Berberine chloride hydrate is an AMPK activator.

Name	berberine hydrochloride hydrate

Description	Berberine chloride hydrate is an alkaloid in several plants with various biological functions, including insulin-sensitizing, anti-inflammatory, and anti-oxidant activity. Berberine chloride hydrate is an AMPK activator.
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> β-catenin Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Stem Cell/Wnt >> Wnt Research Areas >> Cancer
References	[1]. Albring KF, et al. Berberine acts as a natural inhibitor of Wnt/β-catenin signaling--identification of more active 13-arylalkyl derivatives. Biofactors. 2013 Nov-Dec;39(6):652-62. [2]. Jabbarzadeh Kaboli P, et al. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur J Pharmacol. 2014 Jun 26. pii: S0014-2999(14)00467-1. [3]. Wang Y, et al. Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption. Metabolism. 2014 Jun 4. pii: S0026-0495(14)00162-0. [4]. Yu R, et al. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. Cancer Cell Int. 2014 Jun 11;14:49.

Description

Related Catalog

Signaling Pathways >> Stem Cell/Wnt >> β-catenin

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Stem Cell/Wnt >> Wnt

Research Areas >> Cancer

References

[1]. Albring KF, et al. Berberine acts as a natural inhibitor of Wnt/β-catenin signaling--identification of more active 13-arylalkyl derivatives. Biofactors. 2013 Nov-Dec;39(6):652-62.

[2]. Jabbarzadeh Kaboli P, et al. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur J Pharmacol. 2014 Jun 26. pii: S0014-2999(14)00467-1.

[3]. Wang Y, et al. Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption. Metabolism. 2014 Jun 4. pii: S0026-0495(14)00162-0.

[4]. Yu R, et al. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. Cancer Cell Int. 2014 Jun 11;14:49.

Molecular Formula	C₂₀H₂₀ClNO₅
Molecular Weight	389.83000
Exact Mass	389.10300
PSA	50.03000
LogP	3.83400
Storage condition	2-8℃

Berberine chloride hydrate

Use of Berberine chloride hydrate

Names

Berberine chloride hydrate Biological Activity

Chemical & Physical Properties