IWP 12

Modify Date: 2024-01-18 20:51:37

IWP 12 Structure
IWP 12 structure
Common Name IWP 12
CAS Number 688353-45-9 Molecular Weight 418.556
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H18N4O2S3 Melting Point N/A
MSDS USA Flash Point N/A

 Use of IWP 12


IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1].

 Names

Name IWP-12
Synonym More Synonyms

 IWP 12 Biological Activity

Description IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1].
Related Catalog
References

[1]. Wang X, et al. The development of highly potent inhibitors for porcupine. J Med Chem. 2013 Mar 28;56(6):2700-4.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C18H18N4O2S3
Molecular Weight 418.556
Exact Mass 418.059174
LogP 3.99
Index of Refraction 1.783

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

2-[(3,6-Dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-
IWP-12
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